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ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer.
Centenera MM, Scott JS, Machiels J, Nassar ZD, Miller DC, Zinonos I, Dehairs J, Burvenich IJG, Zadra G, Chetta PM, Bango C, Evergren E, Ryan NK, Gillis JL, Mah CY, Tieu T, Hanson AR, Carelli R, Bloch K, Panagopoulos V, Waelkens E, Derua R, Williams ED, Evdokiou A, Cifuentes-Rius A, Voelcker NH, Mills IG, Tilley WD, Scott AM, Loda M, Selth LA, Swinnen JV, Butler LM. Centenera MM, et al. Among authors: panagopoulos v. Cancer Res. 2021 Apr 1;81(7):1704-1718. doi: 10.1158/0008-5472.CAN-20-2511. Epub 2021 Feb 5. Cancer Res. 2021. PMID: 33547161
Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer.
Zinonos I, Luo KW, Labrinidis A, Liapis V, Hay S, Panagopoulos V, Denichilo M, Ko CH, Yue GG, Lau CB, Ingman W, Ponomarev V, Atkins GJ, Findlay DM, Zannettino AC, Evdokiou A. Zinonos I, et al. Among authors: panagopoulos v. Int J Oncol. 2014 Aug;45(2):532-40. doi: 10.3892/ijo.2014.2468. Epub 2014 May 27. Int J Oncol. 2014. PMID: 24865346 Free PMC article.
Hypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma.
Liapis V, Labrinidis A, Zinonos I, Hay S, Ponomarev V, Panagopoulos V, DeNichilo M, Ingman W, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A. Liapis V, et al. Among authors: panagopoulos v. Cancer Lett. 2015 Feb 1;357(1):160-169. doi: 10.1016/j.canlet.2014.11.020. Epub 2014 Nov 15. Cancer Lett. 2015. PMID: 25444931 Free PMC article.
Peroxidase enzymes regulate collagen extracellular matrix biosynthesis.
DeNichilo MO, Panagopoulos V, Rayner TE, Borowicz RA, Greenwood JE, Evdokiou A. DeNichilo MO, et al. Among authors: panagopoulos v. Am J Pathol. 2015 May;185(5):1372-84. doi: 10.1016/j.ajpath.2015.01.013. Epub 2015 Mar 7. Am J Pathol. 2015. PMID: 25759268 Free article.
Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.
Panagopoulos V, Zinonos I, Leach DA, Hay SJ, Liapis V, Zysk A, Ingman WV, DeNichilo MO, Evdokiou A. Panagopoulos V, et al. Int J Biochem Cell Biol. 2015 Nov;68:128-38. doi: 10.1016/j.biocel.2015.09.006. Epub 2015 Sep 18. Int J Biochem Cell Biol. 2015. PMID: 26386352
Peroxidase enzymes inhibit osteoclast differentiation and bone resorption.
Panagopoulos V, Liapis V, Zinonos I, Hay S, Leach DA, Ingman W, DeNichilo MO, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A. Panagopoulos V, et al. Mol Cell Endocrinol. 2017 Jan 15;440:8-15. doi: 10.1016/j.mce.2016.11.007. Epub 2016 Nov 9. Mol Cell Endocrinol. 2017. PMID: 27836774
66 results