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Antibody drug conjugates against the receptor for advanced glycation end products (RAGE), a novel therapeutic target in endometrial cancer.
Healey GD, Pan-Castillo B, Garcia-Parra J, Davies J, Roberts S, Jones E, Dhar K, Nandanan S, Tofazzal N, Piggott L, Clarkson R, Seaton G, Frostell A, Fagge T, McKee C, Margarit L, Conlan RS, Gonzalez D. Healey GD, et al. Among authors: pan castillo b. J Immunother Cancer. 2019 Oct 29;7(1):280. doi: 10.1186/s40425-019-0765-z. J Immunother Cancer. 2019. PMID: 31665084 Free PMC article.
Dinaciclib, a Bimodal Agent Effective against Endometrial Cancer.
Howard D, James D, Murphy K, Garcia-Parra J, Pan-Castillo B, Rex S, Moul A, Jones E, Bilbao-Asensio M, Michue-Seijas S, Lutchman-Singh K, Margarit L, Francis LW, Rees P, Gonzalez D, Conlan RS. Howard D, et al. Among authors: pan castillo b. Cancers (Basel). 2021 Mar 6;13(5):1135. doi: 10.3390/cancers13051135. Cancers (Basel). 2021. PMID: 33800911 Free PMC article.
Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease.
Humphreys DT, Lewis A, Pan-Castillo B, Berti G, Mein C, Wozniak E, Gordon H, Gadhok R, Minicozzi A, ChinAleong J, Feakins R, Giannoulatou E, James LK, Stagg AJ, Lindsay JO, Silver A. Humphreys DT, et al. Among authors: pan castillo b. J Cell Mol Med. 2024 May;28(9):e18344. doi: 10.1111/jcmm.18344. J Cell Mol Med. 2024. PMID: 38685679 Free PMC article.
Epigenetic and metabolic reprogramming of fibroblasts in Crohn's disease strictures reveals histone deacetylases as therapeutic targets.
Lewis A, Humphreys DT, Pan-Castillo B, Berti G, Felice C, Gordon H, Gadhok R, Nijhuis A, Mehta S S, Eleid L, Iqbal S, Armuzzi A, Minicozzi A, Giannoulatou E, ChinAleong J, Feakins R, Sagi-Kiss V, Barisic D, Koufaki MI, Bundy JG, Lindsay JO, Silver A. Lewis A, et al. Among authors: pan castillo b. J Crohns Colitis. 2023 Dec 9:jjad209. doi: 10.1093/ecco-jcc/jjad209. Online ahead of print. J Crohns Colitis. 2023. PMID: 38069679
Dinaciclib as an effective pan-cyclin dependent kinase inhibitor in platinum resistant ovarian cancer.
Howard D, James D, Garcia-Parra J, Pan-Castillo B, Worthington J, Williams N, Coombes Z, Rees SC, Lutchman-Singh K, Francis LW, Rees P, Margarit L, Conlan RS, Gonzalez D. Howard D, et al. Among authors: pan castillo b. Front Oncol. 2022 Nov 25;12:1014280. doi: 10.3389/fonc.2022.1014280. eCollection 2022. Front Oncol. 2022. PMID: 36505806 Free PMC article.