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Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation.
Visnes T, Cázares-Körner A, Hao W, Wallner O, Masuyer G, Loseva O, Mortusewicz O, Wiita E, Sarno A, Manoilov A, Astorga-Wells J, Jemth AS, Pan L, Sanjiv K, Karsten S, Gokturk C, Grube M, Homan EJ, Hanna BMF, Paulin CBJ, Pham T, Rasti A, Berglund UW, von Nicolai C, Benitez-Buelga C, Koolmeister T, Ivanic D, Iliev P, Scobie M, Krokan HE, Baranczewski P, Artursson P, Altun M, Jensen AJ, Kalderén C, Ba X, Zubarev RA, Stenmark P, Boldogh I, Helleday T. Visnes T, et al. Among authors: pan l. Science. 2018 Nov 16;362(6416):834-839. doi: 10.1126/science.aar8048. Science. 2018. PMID: 30442810 Free PMC article.
8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging.
German P, Saenz D, Szaniszlo P, Aguilera-Aguirre L, Pan L, Hegde ML, Bacsi A, Hajas G, Radak Z, Ba X, Mitra S, Papaconstantinou J, Boldogh I. German P, et al. Among authors: pan l. Mech Ageing Dev. 2017 Jan;161(Pt A):51-65. doi: 10.1016/j.mad.2016.06.009. Epub 2016 Jun 21. Mech Ageing Dev. 2017. PMID: 27343030 Free PMC article.
Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation.
Aguilera-Aguirre L, Hao W, Pan L, Li X, Saavedra-Molina A, Bacsi A, Radak Z, Sur S, Brasier AR, Ba X, Boldogh I. Aguilera-Aguirre L, et al. Among authors: pan l. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1058-L1068. doi: 10.1152/ajplung.00141.2017. Epub 2017 Aug 10. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28798252 Free PMC article.
The roles of base excision repair enzyme OGG1 in gene expression.
Wang R, Hao W, Pan L, Boldogh I, Ba X. Wang R, et al. Among authors: pan l. Cell Mol Life Sci. 2018 Oct;75(20):3741-3750. doi: 10.1007/s00018-018-2887-8. Epub 2018 Jul 24. Cell Mol Life Sci. 2018. PMID: 30043138 Free PMC article. Review.
Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid.
Pan L, Wang H, Luo J, Zeng J, Pi J, Liu H, Liu C, Ba X, Qu X, Xiang Y, Boldogh I, Qin X. Pan L, et al. FASEB J. 2019 Dec;33(12):14159-14170. doi: 10.1096/fj.201900993RR. Epub 2019 Oct 25. FASEB J. 2019. PMID: 31652414 Free PMC article.
Data documented here reveal a novel molecular link between OGG1 at damaged sites and transcription dynamics that may contribute to oxidative stress-induced cellular and tissue responses.-Pan, L., Wang, H., Luo, J., Zeng, J., Pi, J., Liu, H., Liu, C., Ba, X., Qu, X., …
Data documented here reveal a novel molecular link between OGG1 at damaged sites and transcription dynamics that may contribute to oxidative …
7,926 results