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Page 1
Mannan-binding lectin modulates the response to HSV-2 infection.
Gadjeva M, Paludan SR, Thiel S, Slavov V, Ruseva M, Eriksson K, Löwhagen GB, Shi L, Takahashi K, Ezekowitz A, Jensenius JC. Gadjeva M, et al. Among authors: paludan sr. Clin Exp Immunol. 2004 Nov;138(2):304-11. doi: 10.1111/j.1365-2249.2004.02616.x. Clin Exp Immunol. 2004. PMID: 15498041 Free PMC article.
An innate antiviral pathway acting before interferons at epithelial surfaces.
Iversen MB, Reinert LS, Thomsen MK, Bagdonaite I, Nandakumar R, Cheshenko N, Prabakaran T, Vakhrushev SY, Krzyzowska M, Kratholm SK, Ruiz-Perez F, Petersen SV, Goriely S, Bibby BM, Eriksson K, Ruland J, Thomsen AR, Herold BC, Wandall HH, Frische S, Holm CK, Paludan SR. Iversen MB, et al. Among authors: paludan sr. Nat Immunol. 2016 Feb;17(2):150-8. doi: 10.1038/ni.3319. Epub 2015 Nov 30. Nat Immunol. 2016. PMID: 26595890
Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-β Expression.
Eriksson K, Svensson A, Hait AS, Schlüter K, Tunbäck P, Nordström I, Padyukov L, Liljeqvist JÅ, Mogensen TH, Paludan SR. Eriksson K, et al. Among authors: paludan sr. J Immunol. 2017 Oct 15;199(8):2613-2617. doi: 10.4049/jimmunol.1700385. Epub 2017 Sep 11. J Immunol. 2017. PMID: 28893956
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.
Olagnier D, Farahani E, Thyrsted J, Blay-Cadanet J, Herengt A, Idorn M, Hait A, Hernaez B, Knudsen A, Iversen MB, Schilling M, Jørgensen SE, Thomsen M, Reinert LS, Lappe M, Hoang HD, Gilchrist VH, Hansen AL, Ottosen R, Nielsen CG, Møller C, van der Horst D, Peri S, Balachandran S, Huang J, Jakobsen M, Svenningsen EB, Poulsen TB, Bartsch L, Thielke AL, Luo Y, Alain T, Rehwinkel J, Alcamí A, Hiscott J, Mogensen TH, Paludan SR, Holm CK. Olagnier D, et al. Among authors: paludan sr. Nat Commun. 2020 Oct 2;11(1):4938. doi: 10.1038/s41467-020-18764-3. Nat Commun. 2020. PMID: 33009401 Free PMC article.
Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro.
Svenningsen EB, Thyrsted J, Blay-Cadanet J, Liu H, Lin S, Moyano-Villameriel J, Olagnier D, Idorn M, Paludan SR, Holm CK, Poulsen TB. Svenningsen EB, et al. Among authors: paludan sr. Antiviral Res. 2021 Jan;185:104988. doi: 10.1016/j.antiviral.2020.104988. Epub 2020 Nov 25. Antiviral Res. 2021. PMID: 33248195 Free PMC article.
Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans.
Hait AS, Olagnier D, Sancho-Shimizu V, Skipper KA, Helleberg M, Larsen SM, Bodda C, Moldovan LI, Ren F, Brinck Andersen NS, Thomsen MM, Freytag MR, Darmalinggam S, Parkes I, Kadekar DD, Rahbek SH, van der Horst D, Kristensen LS, Eriksson K, Kjems J, Mostowy S, Christiansen M, Mikkelsen JG, Brandt CT, Paludan SR, Mogensen TH. Hait AS, et al. Among authors: paludan sr. Sci Immunol. 2020 Dec 11;5(54):eabc2691. doi: 10.1126/sciimmunol.abc2691. Sci Immunol. 2020. PMID: 33310865 Free PMC article.
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity.
Fougeroux C, Goksøyr L, Idorn M, Soroka V, Myeni SK, Dagil R, Janitzek CM, Søgaard M, Aves KL, Horsted EW, Erdoğan SM, Gustavsson T, Dorosz J, Clemmensen S, Fredsgaard L, Thrane S, Vidal-Calvo EE, Khalifé P, Hulen TM, Choudhary S, Theisen M, Singh SK, Garcia-Senosiain A, Van Oosten L, Pijlman G, Hierzberger B, Domeyer T, Nalewajek BW, Strøbæk A, Skrzypczak M, Andersson LF, Buus S, Buus AS, Christensen JP, Dalebout TJ, Iversen K, Harritshøj LH, Mordmüller B, Ullum H, Reinert LS, de Jongh WA, Kikkert M, Paludan SR, Theander TG, Nielsen MA, Salanti A, Sander AF. Fougeroux C, et al. Among authors: paludan sr. Nat Commun. 2021 Jan 12;12(1):324. doi: 10.1038/s41467-020-20251-8. Nat Commun. 2021. PMID: 33436573 Free PMC article.
SARS-CoV-2 Neutralizing Antibody Responses towards Full-Length Spike Protein and the Receptor-Binding Domain.
Bayarri-Olmos R, Idorn M, Rosbjerg A, Pérez-Alós L, Hansen CB, Johnsen LB, Helgstrand C, Zosel F, Bjelke JR, Öberg FK, Søgaard M, Paludan SR, Bak-Thomsen T, Jardine JG, Skjoedt MO, Garred P. Bayarri-Olmos R, et al. Among authors: paludan sr. J Immunol. 2021 Aug 1;207(3):878-887. doi: 10.4049/jimmunol.2100272. Epub 2021 Jul 23. J Immunol. 2021. PMID: 34301847
198 results