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Tetrahydrocannabinolic acid is a potent PPARγ agonist with neuroprotective activity.
Nadal X, Del Río C, Casano S, Palomares B, Ferreiro-Vera C, Navarrete C, Sánchez-Carnerero C, Cantarero I, Bellido ML, Meyer S, Morello G, Appendino G, Muñoz E. Nadal X, et al. Among authors: palomares b. Br J Pharmacol. 2017 Dec;174(23):4263-4276. doi: 10.1111/bph.14019. Epub 2017 Nov 2. Br J Pharmacol. 2017. PMID: 28853159 Free PMC article.
VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington's disease.
Díaz-Alonso J, Paraíso-Luna J, Navarrete C, Del Río C, Cantarero I, Palomares B, Aguareles J, Fernández-Ruiz J, Bellido ML, Pollastro F, Appendino G, Calzado MA, Galve-Roperh I, Muñoz E. Díaz-Alonso J, et al. Among authors: palomares b. Sci Rep. 2016 Jul 19;6:29789. doi: 10.1038/srep29789. Sci Rep. 2016. PMID: 27430371 Free PMC article.
VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways.
Del Rio C, Cantarero I, Palomares B, Gómez-Cañas M, Fernández-Ruiz J, Pavicic C, García-Martín A, Luz Bellido M, Ortega-Castro R, Pérez-Sánchez C, López-Pedrera C, Appendino G, Calzado MA, Muñoz E. Del Rio C, et al. Among authors: palomares b. Br J Pharmacol. 2018 Oct;175(19):3813-3831. doi: 10.1111/bph.14450. Epub 2018 Aug 23. Br J Pharmacol. 2018. PMID: 30033591 Free PMC article.
Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity.
Palomares B, Ruiz-Pino F, Garrido-Rodriguez M, Eugenia Prados M, Sánchez-Garrido MA, Velasco I, Vazquez MJ, Nadal X, Ferreiro-Vera C, Morrugares R, Appendino G, Calzado MA, Tena-Sempere M, Muñoz E. Palomares B, et al. Biochem Pharmacol. 2020 Jan;171:113693. doi: 10.1016/j.bcp.2019.113693. Epub 2019 Nov 9. Biochem Pharmacol. 2020. PMID: 31706843 Free article.
Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson's disease: possible involvement of different binding sites at the PPARγ receptor.
García C, Gómez-Cañas M, Burgaz S, Palomares B, Gómez-Gálvez Y, Palomo-Garo C, Campo S, Ferrer-Hernández J, Pavicic C, Navarrete C, Luz Bellido M, García-Arencibia M, Ruth Pazos M, Muñoz E, Fernández-Ruiz J. García C, et al. Among authors: palomares b. J Neuroinflammation. 2018 Jan 16;15(1):19. doi: 10.1186/s12974-018-1060-5. J Neuroinflammation. 2018. PMID: 29338785 Free PMC article.
Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy.
Navarrete C, Carrillo-Salinas F, Palomares B, Mecha M, Jiménez-Jiménez C, Mestre L, Feliú A, Bellido ML, Fiebich BL, Appendino G, Calzado MA, Guaza C, Muñoz E. Navarrete C, et al. Among authors: palomares b. J Neuroinflammation. 2018 Mar 1;15(1):64. doi: 10.1186/s12974-018-1103-y. J Neuroinflammation. 2018. PMID: 29495967 Free PMC article.
Effect of N-acyl-dopamines on beta cell differentiation and wound healing in diabetic mice.
Jiménez-Jiménez C, Lara-Chica M, Palomares B, Collado JA, Lopez-Miranda J, Muñoz E, Calzado MA. Jiménez-Jiménez C, et al. Among authors: palomares b. Biochim Biophys Acta Mol Cell Res. 2018 Nov;1865(11 Pt A):1539-1551. doi: 10.1016/j.bbamcr.2018.08.008. Epub 2018 Aug 16. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 30327197 Free article.
15 results