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A genome-wide CRISPR-Cas9 knockout screen identifies novel PARP inhibitor resistance genes in prostate cancer.
Ipsen MB, Sørensen EMG, Thomsen EA, Weiss S, Haldrup J, Dalby A, Palmfeldt J, Bross P, Rasmussen M, Fredsøe J, Klingenberg S, Jochumsen MR, Bouchelouche K, Ulhøi BP, Borre M, Mikkelsen JG, Sørensen KD. Ipsen MB, et al. Among authors: palmfeldt j. Oncogene. 2022 Sep;41(37):4271-4281. doi: 10.1038/s41388-022-02427-2. Epub 2022 Aug 6. Oncogene. 2022. PMID: 35933519
The Hsp60-(p.V98I) mutation associated with hereditary spastic paraplegia SPG13 compromises chaperonin function both in vitro and in vivo.
Bross P, Naundrup S, Hansen J, Nielsen MN, Christensen JH, Kruhøffer M, Palmfeldt J, Corydon TJ, Gregersen N, Ang D, Georgopoulos C, Nielsen KL. Bross P, et al. Among authors: palmfeldt j. J Biol Chem. 2008 Jun 6;283(23):15694-700. doi: 10.1074/jbc.M800548200. Epub 2008 Apr 8. J Biol Chem. 2008. PMID: 18400758 Free PMC article.
A cell model to study different degrees of Hsp60 deficiency in HEK293 cells.
Bie AS, Palmfeldt J, Hansen J, Christensen R, Gregersen N, Corydon TJ, Bross P. Bie AS, et al. Among authors: palmfeldt j. Cell Stress Chaperones. 2011 Nov;16(6):633-40. doi: 10.1007/s12192-011-0275-5. Epub 2011 Jun 30. Cell Stress Chaperones. 2011. PMID: 21717087 Free PMC article.
Quantitative proteomics reveals cellular targets of celastrol.
Hansen J, Palmfeldt J, Vang S, Corydon TJ, Gregersen N, Bross P. Hansen J, et al. Among authors: palmfeldt j. PLoS One. 2011;6(10):e26634. doi: 10.1371/journal.pone.0026634. Epub 2011 Oct 26. PLoS One. 2011. PMID: 22046318 Free PMC article.
Heterozygosity for an in-frame deletion causes glutaryl-CoA dehydrogenase deficiency in a patient detected by newborn screening: investigation of the effect of the mutant allele.
Bross P, Frederiksen JB, Bie AS, Hansen J, Palmfeldt J, Nielsen MN, Duno M, Lund AM, Christensen E. Bross P, et al. Among authors: palmfeldt j. J Inherit Metab Dis. 2012 Sep;35(5):787-96. doi: 10.1007/s10545-011-9437-y. Epub 2012 Jan 10. J Inherit Metab Dis. 2012. PMID: 22231382
Mutated desmoglein-2 proteins are incorporated into desmosomes and exhibit dominant-negative effects in arrhythmogenic right ventricular cardiomyopathy.
Rasmussen TB, Palmfeldt J, Nissen PH, Magnoni R, Dalager S, Jensen UB, Kim WY, Heickendorff L, Mølgaard H, Jensen HK, Baandrup UT, Bross P, Mogensen J. Rasmussen TB, et al. Among authors: palmfeldt j. Hum Mutat. 2013 May;34(5):697-705. doi: 10.1002/humu.22289. Epub 2013 Mar 11. Hum Mutat. 2013. PMID: 23381804
106 results