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DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors.
Chamakuri S, Lu S, Ucisik MN, Bohren KM, Chen YC, Du HC, Faver JC, Jimmidi R, Li F, Li JY, Nyshadham P, Palmer SS, Pollet J, Qin X, Ronca SE, Sankaran B, Sharma KL, Tan Z, Versteeg L, Yu Z, Matzuk MM, Palzkill T, Young DW. Chamakuri S, et al. Among authors: palmer ss. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2111172118. doi: 10.1073/pnas.2111172118. Proc Natl Acad Sci U S A. 2021. PMID: 34426525 Free PMC article.
Discovery and characterization of bromodomain 2-specific inhibitors of BRDT.
Yu Z, Ku AF, Anglin JL, Sharma R, Ucisik MN, Faver JC, Li F, Nyshadham P, Simmons N, Sharma KL, Nagarajan S, Riehle K, Kaur G, Sankaran B, Storl-Desmond M, Palmer SS, Young DW, Kim C, Matzuk MM. Yu Z, et al. Among authors: palmer ss. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2021102118. doi: 10.1073/pnas.2021102118. Proc Natl Acad Sci U S A. 2021. PMID: 33637650 Free PMC article.
Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections.
Modukuri RK, Yu Z, Tan Z, Ta HM, Ucisik MN, Jin Z, Anglin JL, Sharma KL, Nyshadham P, Li F, Riehle K, Faver JC, Duong K, Nagarajan S, Simmons N, Palmer SS, Teng M, Young DW, Yi JS, Kim C, Matzuk MM. Modukuri RK, et al. Among authors: palmer ss. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2122506119. doi: 10.1073/pnas.2122506119. Epub 2022 May 27. Proc Natl Acad Sci U S A. 2022. PMID: 35622893 Free PMC article.
Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor.
De Pascali F, Ayoub MA, Benevelli R, Sposini S, Lehoux J, Gallay N, Raynaud P, Landomiel F, Jean-Alphonse F, Gauthier C, Pellissier LP, Crépieux P, Poupon A, Inoue A, Joubert N, Viaud-Massuard MC, Casarini L, Simoni M, Hanyaloglu AC, Nataraja SG, Yu HN, Palmer SS, Yvinec R, Reiter E. De Pascali F, et al. Among authors: palmer ss. Int J Mol Sci. 2021 Sep 12;22(18):9850. doi: 10.3390/ijms22189850. Int J Mol Sci. 2021. PMID: 34576014 Free PMC article.
37 results