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Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses.
Nguyen LC, Yang D, Nicolaescu V, Best TJ, Gula H, Saxena D, Gabbard JD, Chen SN, Ohtsuki T, Friesen JB, Drayman N, Mohamed A, Dann C, Silva D, Robinson-Mailman L, Valdespino A, Stock L, Suárez E, Jones KA, Azizi SA, Demarco JK, Severson WE, Anderson CD, Millis JM, Dickinson BC, Tay S, Oakes SA, Pauli GF, Palmer KE; National COVID Cohort Collaborative Consortium; Meltzer DO, Randall G, Rosner MR. Nguyen LC, et al. Among authors: palmer ke. Sci Adv. 2022 Feb 25;8(8):eabi6110. doi: 10.1126/sciadv.abi6110. Epub 2022 Feb 23. Sci Adv. 2022. PMID: 35050692 Free article.
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.
Drayman N, DeMarco JK, Jones KA, Azizi SA, Froggatt HM, Tan K, Maltseva NI, Chen S, Nicolaescu V, Dvorkin S, Furlong K, Kathayat RS, Firpo MR, Mastrodomenico V, Bruce EA, Schmidt MM, Jedrzejczak R, Muñoz-Alía MÁ, Schuster B, Nair V, Han KY, O'Brien A, Tomatsidou A, Meyer B, Vignuzzi M, Missiakas D, Botten JW, Brooke CB, Lee H, Baker SC, Mounce BC, Heaton NS, Severson WE, Palmer KE, Dickinson BC, Joachimiak A, Randall G, Tay S. Drayman N, et al. Among authors: palmer ke. Science. 2021 Aug 20;373(6557):931-936. doi: 10.1126/science.abg5827. Epub 2021 Jul 20. Science. 2021. PMID: 34285133 Free PMC article.
CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology.
DeMarco JK, Royal JM, Severson WE, Gabbard JD, Hume S, Morton J, Swope K, Simpson CA, Shepherd JW, Bratcher B, Palmer KE, Pogue GP. DeMarco JK, et al. Among authors: palmer ke. Vaccines (Basel). 2021 Nov 17;9(11):1346. doi: 10.3390/vaccines9111346. Vaccines (Basel). 2021. PMID: 34835277 Free PMC article.
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.
Teng Y, Xu F, Zhang X, Mu J, Sayed M, Hu X, Lei C, Sriwastva M, Kumar A, Sundaram K, Zhang L, Park JW, Chen SY, Zhang S, Yan J, Merchant ML, Zhang X, McClain CJ, Wolfe JK, Adcock RS, Chung D, Palmer KE, Zhang HG. Teng Y, et al. Among authors: palmer ke. Mol Ther. 2021 Aug 4;29(8):2424-2440. doi: 10.1016/j.ymthe.2021.05.005. Epub 2021 May 11. Mol Ther. 2021. PMID: 33984520 Free PMC article.
Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients.
Rouchka EC, Chariker JH, Alejandro B, Adcock RS, Singhal R, Ramirez J, Palmer KE, Lasnik AB, Carrico R, Arnold FW, Furmanek S, Zhang M, Wolf LA, Waigel S, Zacharias W, Bordon J, Chung D. Rouchka EC, et al. Among authors: palmer ke. Sci Rep. 2021 Aug 3;11(1):15715. doi: 10.1038/s41598-021-95197-y. Sci Rep. 2021. PMID: 34344959 Free PMC article.
Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge.
Lo MK, Spengler JR, Krumpe LRH, Welch SR, Chattopadhyay A, Harmon JR, Coleman-McCray JD, Scholte FEM, Hotard AL, Fuqua JL, Rose JK, Nichol ST, Palmer KE, O'Keefe BR, Spiropoulou CF. Lo MK, et al. Among authors: palmer ke. J Infect Dis. 2020 May 11;221(Supplement_4):S480-S492. doi: 10.1093/infdis/jiz630. J Infect Dis. 2020. PMID: 32037447 Free PMC article.
82 results