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Griffithsin has antiviral activity against hepatitis C virus.
Meuleman P, Albecka A, Belouzard S, Vercauteren K, Verhoye L, Wychowski C, Leroux-Roels G, Palmer KE, Dubuisson J. Meuleman P, et al. Among authors: palmer ke. Antimicrob Agents Chemother. 2011 Nov;55(11):5159-67. doi: 10.1128/AAC.00633-11. Epub 2011 Sep 6. Antimicrob Agents Chemother. 2011. PMID: 21896910 Free PMC article.
Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models.
Barton C, Kouokam JC, Lasnik AB, Foreman O, Cambon A, Brock G, Montefiori DC, Vojdani F, McCormick AA, O'Keefe BR, Palmer KE. Barton C, et al. Among authors: palmer ke. Antimicrob Agents Chemother. 2014;58(1):120-7. doi: 10.1128/AAC.01407-13. Epub 2013 Oct 21. Antimicrob Agents Chemother. 2014. PMID: 24145548 Free PMC article.
Griffithsin-Modified Electrospun Fibers as a Delivery Scaffold To Prevent HIV Infection.
Grooms TN, Vuong HR, Tyo KM, Malik DA, Sims LB, Whittington CP, Palmer KE, Matoba N, Steinbach-Rankins JM. Grooms TN, et al. Among authors: palmer ke. Antimicrob Agents Chemother. 2016 Oct 21;60(11):6518-6531. doi: 10.1128/AAC.00956-16. Print 2016 Nov. Antimicrob Agents Chemother. 2016. PMID: 27550363 Free PMC article.
Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice.
Banerjee K, Michael E, Eggink D, van Montfort T, Lasnik AB, Palmer KE, Sanders RW, Moore JP, Klasse PJ. Banerjee K, et al. Among authors: palmer ke. AIDS Res Hum Retroviruses. 2012 Feb;28(2):206-14. doi: 10.1089/aid.2011.0101. Epub 2011 Jul 27. AIDS Res Hum Retroviruses. 2012. PMID: 21793733 Free PMC article.
Efficient single tobamoviral vector-based bioproduction of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 in Nicotiana benthamiana plants and utility of VRC01 in combination microbicides.
Hamorsky KT, Grooms-Williams TW, Husk AS, Bennett LJ, Palmer KE, Matoba N. Hamorsky KT, et al. Among authors: palmer ke. Antimicrob Agents Chemother. 2013 May;57(5):2076-86. doi: 10.1128/AAC.02588-12. Epub 2013 Feb 12. Antimicrob Agents Chemother. 2013. PMID: 23403432 Free PMC article.
Combinations of griffithsin with other carbohydrate-binding agents demonstrate superior activity against HIV Type 1, HIV Type 2, and selected carbohydrate-binding agent-resistant HIV Type 1 strains.
Férir G, Huskens D, Palmer KE, Boudreaux DM, Swanson MD, Markovitz DM, Balzarini J, Schols D. Férir G, et al. Among authors: palmer ke. AIDS Res Hum Retroviruses. 2012 Nov;28(11):1513-23. doi: 10.1089/AID.2012.0026. Epub 2012 Jun 25. AIDS Res Hum Retroviruses. 2012. PMID: 22607556 Free PMC article.
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