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Collapse of the tumor stroma is triggered by IL-12 induction of Fas.
Kerkar SP, Leonardi AJ, van Panhuys N, Zhang L, Yu Z, Crompton JG, Pan JH, Palmer DC, Morgan RA, Rosenberg SA, Restifo NP. Kerkar SP, et al. Among authors: palmer dc. Mol Ther. 2013 Jul;21(7):1369-77. doi: 10.1038/mt.2013.58. Epub 2013 Apr 9. Mol Ther. 2013. PMID: 23568260 Free PMC article.
Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts.
Kerkar SP, Muranski P, Kaiser A, Boni A, Sanchez-Perez L, Yu Z, Palmer DC, Reger RN, Borman ZA, Zhang L, Morgan RA, Gattinoni L, Rosenberg SA, Trinchieri G, Restifo NP. Kerkar SP, et al. Among authors: palmer dc. Cancer Res. 2010 Sep 1;70(17):6725-34. doi: 10.1158/0008-5472.CAN-10-0735. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647327 Free PMC article.
Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics.
Crompton JG, Sukumar M, Roychoudhuri R, Clever D, Gros A, Eil RL, Tran E, Hanada K, Yu Z, Palmer DC, Kerkar SP, Michalek RD, Upham T, Leonardi A, Acquavella N, Wang E, Marincola FM, Gattinoni L, Muranski P, Sundrud MS, Klebanoff CA, Rosenberg SA, Fearon DT, Restifo NP. Crompton JG, et al. Among authors: palmer dc. Cancer Res. 2015 Jan 15;75(2):296-305. doi: 10.1158/0008-5472.CAN-14-2277. Epub 2014 Nov 28. Cancer Res. 2015. PMID: 25432172 Free PMC article.
Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules.
Rodriguez-Peña AB, Gomez-Rodriguez J, Kortum RL, Palmer DC, Yu Z, Guittard GC, Wohlfert EA, Silver PB, Misplon JA, Sommers CL, Feigenbaum L, Epstein SL, Caspi RR, Belkaid Y, Restifo NP, Samelson LE, Balagopalan L. Rodriguez-Peña AB, et al. Among authors: palmer dc. Gene Ther. 2015 Oct;22(10):781-92. doi: 10.1038/gt.2015.48. Epub 2015 Jun 18. Gene Ther. 2015. PMID: 26018935 Free PMC article.
Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.
Overwijk WW, Theoret MR, Finkelstein SE, Surman DR, de Jong LA, Vyth-Dreese FA, Dellemijn TA, Antony PA, Spiess PJ, Palmer DC, Heimann DM, Klebanoff CA, Yu Z, Hwang LN, Feigenbaum L, Kruisbeek AM, Rosenberg SA, Restifo NP. Overwijk WW, et al. Among authors: palmer dc. J Exp Med. 2003 Aug 18;198(4):569-80. doi: 10.1084/jem.20030590. J Exp Med. 2003. PMID: 12925674 Free PMC article.
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells.
Klebanoff CA, Finkelstein SE, Surman DR, Lichtman MK, Gattinoni L, Theoret MR, Grewal N, Spiess PJ, Antony PA, Palmer DC, Tagaya Y, Rosenberg SA, Waldmann TA, Restifo NP. Klebanoff CA, et al. Among authors: palmer dc. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1969-74. doi: 10.1073/pnas.0307298101. Epub 2004 Feb 4. Proc Natl Acad Sci U S A. 2004. PMID: 14762166 Free PMC article.
Bedside to bench and back again: how animal models are guiding the development of new immunotherapies for cancer.
Finkelstein SE, Heimann DM, Klebanoff CA, Antony PA, Gattinoni L, Hinrichs CS, Hwang LN, Palmer DC, Spiess PJ, Surman DR, Wrzesiniski C, Yu Z, Rosenberg SA, Restifo NP. Finkelstein SE, et al. Among authors: palmer dc. J Leukoc Biol. 2004 Aug;76(2):333-7. doi: 10.1189/jlb.0304120. Epub 2004 May 20. J Leukoc Biol. 2004. PMID: 15155774 Free PMC article.
117 results