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A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses.
Markert JM, Razdan SN, Kuo HC, Cantor A, Knoll A, Karrasch M, Nabors LB, Markiewicz M, Agee BS, Coleman JM, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Weichselbaum RR, Fiveash JB, Gillespie GY. Markert JM, et al. Among authors: palmer ca. Mol Ther. 2014 May;22(5):1048-55. doi: 10.1038/mt.2014.22. Epub 2014 Feb 27. Mol Ther. 2014. PMID: 24572293 Free PMC article. Clinical Trial.
Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM).
Grunda JM, Nabors LB, Palmer CA, Chhieng DC, Steg A, Mikkelsen T, Diasio RB, Zhang K, Allison D, Grizzle WE, Wang W, Gillespie GY, Johnson MR. Grunda JM, et al. Among authors: palmer ca. J Neurooncol. 2006 Dec;80(3):261-74. doi: 10.1007/s11060-006-9191-4. Epub 2006 Jun 14. J Neurooncol. 2006. PMID: 16773218
The safety of OP-1 for lumbar fusion with decompression-- a canine study.
Paramore CG, Lauryssen C, Rauzzino MJ, Wadlington VR, Palmer CA, Brix A, Cartner SC, Hadley MN. Paramore CG, et al. Among authors: palmer ca. Neurosurgery. 1999 May;44(5):1151-5; discussion 1155-6. doi: 10.1097/00006123-199905000-00134. Neurosurgery. 1999. PMID: 10232555
223 results