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Insulin feedback is a targetable resistance mechanism of PI3K inhibition in glioblastoma.
Neuro Oncol. 2023 Dec 8;25(12):2165-2176. doi: 10.1093/neuonc/noad117.
Neuro Oncol. 2023.
PMID: 37399061
Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production.
Noch EK, Palma L, Yim I, Bullen N, Barnett D, Walsh A, Bhinder B, Benedetti E, Krumsiek J, Gurvitch J, Khwaja S, Atlas D, Elemento O, Cantley LC.
Noch EK, et al.
Proc Natl Acad Sci U S A. 2024 Feb 20;121(8):e2317343121. doi: 10.1073/pnas.2317343121. Epub 2024 Feb 15.
Proc Natl Acad Sci U S A. 2024.
PMID: 38359293
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