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Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells.
Gargaro M, Vacca C, Massari S, Scalisi G, Manni G, Mondanelli G, Mazza EMC, Bicciato S, Pallotta MT, Orabona C, Belladonna ML, Volpi C, Bianchi R, Matino D, Iacono A, Panfili E, Proietti E, Iamandii IM, Cecchetti V, Puccetti P, Tabarrini O, Fallarino F, Grohmann U. Gargaro M, et al. Among authors: pallotta mt. Front Immunol. 2019 Aug 20;10:1973. doi: 10.3389/fimmu.2019.01973. eCollection 2019. Front Immunol. 2019. PMID: 31481962 Free PMC article.
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.
Mondanelli G, Coletti A, Greco FA, Pallotta MT, Orabona C, Iacono A, Belladonna ML, Albini E, Panfili E, Fallarino F, Gargaro M, Manni G, Matino D, Carvalho A, Cunha C, Maciel P, Di Filippo M, Gaetani L, Bianchi R, Vacca C, Iamandii IM, Proietti E, Boscia F, Annunziato L, Peppelenbosch M, Puccetti P, Calabresi P, Macchiarulo A, Santambrogio L, Volpi C, Grohmann U. Mondanelli G, et al. Among authors: pallotta mt. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3848-3857. doi: 10.1073/pnas.1918215117. Epub 2020 Feb 5. Proc Natl Acad Sci U S A. 2020. PMID: 32024760 Free PMC article.
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity.
Serafini M, Torre E, Aprile S, Grosso ED, Gesù A, Griglio A, Colombo G, Travelli C, Paiella S, Adamo A, Orecchini E, Coletti A, Pallotta MT, Ugel S, Massarotti A, Pirali T, Fallarini S. Serafini M, et al. Among authors: pallotta mt. J Med Chem. 2020 Mar 26;63(6):3047-3065. doi: 10.1021/acs.jmedchem.9b01809. Epub 2020 Mar 17. J Med Chem. 2020. PMID: 32150677
Amino Acid Metabolism in Rheumatoid Arthritis: Friend or Foe?
Panfili E, Gerli R, Grohmann U, Pallotta MT. Panfili E, et al. Among authors: pallotta mt. Biomolecules. 2020 Sep 4;10(9):1280. doi: 10.3390/biom10091280. Biomolecules. 2020. PMID: 32899743 Free PMC article. Review.
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1.
Iacono A, Pompa A, De Marchis F, Panfili E, Greco FA, Coletti A, Orabona C, Volpi C, Belladonna ML, Mondanelli G, Albini E, Vacca C, Gargaro M, Fallarino F, Bianchi R, De Marcos Lousa C, Mazza EM, Bicciato S, Proietti E, Milano F, Martelli MP, Iamandii IM, Graupera Garcia-Mila M, Llena Sopena J, Hawkins P, Suire S, Okkenhaug K, Stark AK, Grassi F, Bellucci M, Puccetti P, Santambrogio L, Macchiarulo A, Grohmann U, Pallotta MT. Iacono A, et al. Among authors: pallotta mt. EMBO Rep. 2020 Dec 3;21(12):e49756. doi: 10.15252/embr.201949756. Epub 2020 Nov 7. EMBO Rep. 2020. PMID: 33159421 Free PMC article.
Moonlighting Proteins Are Important Players in Cancer Immunology.
Adamo A, Frusteri C, Pallotta MT, Pirali T, Sartoris S, Ugel S. Adamo A, et al. Among authors: pallotta mt. Front Immunol. 2021 Jan 18;11:613069. doi: 10.3389/fimmu.2020.613069. eCollection 2020. Front Immunol. 2021. PMID: 33584695 Free PMC article. Review.
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation.
Panfili E, Mondanelli G, Orabona C, Belladonna ML, Gargaro M, Fallarino F, Orecchini E, Prontera P, Proietti E, Frontino G, Tirelli E, Iacono A, Vacca C, Puccetti P, Grohmann U, Esposito S, Pallotta MT. Panfili E, et al. Among authors: pallotta mt. Hum Mol Genet. 2021 Apr 26;30(3-4):265-276. doi: 10.1093/hmg/ddab040. Hum Mol Genet. 2021. PMID: 33693650 Free PMC article.
63 results