Palin R - Search Results

1

A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host.

Bom A, Bradley M, Cameron K, Clark JK, Van Egmond J, Feilden H, MacLean EJ, Muir AW, Palin R, Rees DC, Zhang MQ. Bom A, et al. Among authors: palin r. Angew Chem Int Ed Engl. 2002 Jan 18;41(2):266-70. doi: 10.1002/1521-3773(20020118)41:2<265::aid-anie265>3.0.co;2-q. Angew Chem Int Ed Engl. 2002. PMID: 12491405 No abstract available.

2

Cyclodextrin-derived host molecules as reversal agents for the neuromuscular blocker rocuronium bromide: synthesis and structure-activity relationships.

Adam JM, Bennett DJ, Bom A, Clark JK, Feilden H, Hutchinson EJ, Palin R, Prosser A, Rees DC, Rosair GM, Stevenson D, Tarver GJ, Zhang MQ. Adam JM, et al. Among authors: palin r. J Med Chem. 2002 Apr 25;45(9):1806-16. doi: 10.1021/jm011107f. J Med Chem. 2002. PMID: 11960492

3

New approaches to reversal of neuromuscular block.

Bom A, Clark JK, Palin R. Bom A, et al. Among authors: palin r. Curr Opin Drug Discov Devel. 2002 Sep;5(5):793-800. Curr Opin Drug Discov Devel. 2002. PMID: 12630300 Review.

4

Mutual induced fit in cyclodextrin-rocuronium complexes.

Cooper A, Nutley M, MacLean EJ, Cameron K, Fielding L, Mestres J, Palin R. Cooper A, et al. Among authors: palin r. Org Biomol Chem. 2005 May 21;3(10):1863-71. doi: 10.1039/b415903a. Epub 2005 Mar 23. Org Biomol Chem. 2005. PMID: 15889169

5

Modified gamma-cyclodextrins and their rocuronium complexes.

Cameron KS, Clark JK, Cooper A, Fielding L, Palin R, Rutherford SJ, Zhang MQ. Cameron KS, et al. Among authors: palin r. Org Lett. 2002 Oct 3;4(20):3403-6. doi: 10.1021/ol020126w. Org Lett. 2002. PMID: 12323029

6

Quaternary salts of E2020 analogues as acetylcholinesterase inhibitors for the reversal of neuromuscular block.

Clark JK, Cowley P, Muir AW, Palin R, Pow E, Prosser AB, Taylor R, Zhang MQ. Clark JK, et al. Among authors: palin r. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2565-8. doi: 10.1016/s0960-894x(02)00482-1. Bioorg Med Chem Lett. 2002. PMID: 12182861

7

Novel piperidinium and pyridinium agents as water-soluble acetylcholinesterase inhibitors for the reversal of neuromuscular blockade.

Palin R, Clark JK, Cowley P, Muir AW, Pow E, Prosser AB, Taylor R, Zhang MQ. Palin R, et al. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2569-72. doi: 10.1016/s0960-894x(02)00483-3. Bioorg Med Chem Lett. 2002. PMID: 12182862

8

Synthesis and evaluation of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic and sedative properties.

Palin R, Bom A, Clark JK, Evans L, Feilden H, Houghton AK, Jones PS, Montgomery B, Weston MA, Wishart G. Palin R, et al. Bioorg Med Chem. 2007 Feb 15;15(4):1828-47. doi: 10.1016/j.bmc.2006.11.030. Epub 2006 Nov 19. Bioorg Med Chem. 2007. PMID: 17166723

9

NMR spectra and dynamics of the sodium salt of per(6-thiobenzoic acid)-gamma-cyclodextrin.

Cameron KS, Fielding L, Palin R, Uhrin D. Cameron KS, et al. Among authors: palin r. Magn Reson Chem. 2005 Aug;43(8):647-53. doi: 10.1002/mrc.1599. Magn Reson Chem. 2005. PMID: 15915545

10

Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists.

Palin R, Barn DR, Clark JK, Cottney JE, Cowley PM, Crockatt M, Evans L, Feilden H, Goodwin RR, Griekspoor F, Grove SJ, Houghton AK, Jones PS, Morphy RJ, Smith AR, Sundaram H, Vrolijk D, Weston MA, Wishart G, Wren P. Palin R, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):589-93. doi: 10.1016/j.bmcl.2004.11.049. Bioorg Med Chem Lett. 2005. PMID: 15664818

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