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α-Aminophosphonate inhibitors of metallo-β-lactamases NDM-1 and VIM-2.
Palica K, Deufel F, Skagseth S, Di Santo Metzler GP, Thoma J, Andersson Rasmussen A, Valkonen A, Sunnerhagen P, Leiros HS, Andersson H, Erdelyi M. Palica K, et al. RSC Med Chem. 2023 Aug 2;14(11):2277-2300. doi: 10.1039/d3md00286a. eCollection 2023 Nov 15. RSC Med Chem. 2023. PMID: 38020072 Free PMC article.
Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters.
Palica K, Vorácová M, Skagseth S, Andersson Rasmussen A, Allander L, Hubert M, Sandegren L, Schrøder Leiros HK, Andersson H, Erdélyi M. Palica K, et al. ACS Omega. 2022 Jan 25;7(5):4550-4562. doi: 10.1021/acsomega.1c06527. eCollection 2022 Feb 8. ACS Omega. 2022. PMID: 35155946 Free PMC article.
Discovery of a series of ester-substituted NLRP3 inflammasome inhibitors.
Harrison D, Boutard N, Brzozka K, Bugaj M, Chmielewski S, Cierpich A, Doedens JR, Fabritius CRY, Gabel CA, Galezowski M, Kowalczyk P, Levenets O, Mroczkowska M, Palica K, Porter RA, Schultz D, Sowinska M, Topolnicki G, Urbanski P, Woyciechowski J, Watt AP. Harrison D, et al. Among authors: palica k. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127560. doi: 10.1016/j.bmcl.2020.127560. Epub 2020 Sep 18. Bioorg Med Chem Lett. 2020. PMID: 32956781