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Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes.
Pagire SH, Pagire HS, Lee GB, Han SJ, Kwak HJ, Kim JY, Kim KY, Rhee SD, Ryu JI, Song JS, Bae MA, Park MJ, Kim D, Lee DH, Ahn JH. Pagire SH, et al. Among authors: pagire hs. Eur J Med Chem. 2015 Aug 28;101:716-35. doi: 10.1016/j.ejmech.2015.06.043. Epub 2015 Jun 27. Eur J Med Chem. 2015. PMID: 26218650
Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases.
Lee D, Pagire HS, Pagire SH, Bae EJ, Dighe M, Kim M, Lee KM, Jang YK, Jaladi AK, Jung KY, Yoo EK, Gim HE, Lee S, Choi WI, Chi YI, Song JS, Bae MA, Jeon YH, Lee GH, Liu KH, Lee T, Park S, Jeon JH, Lee IK, Ahn JH. Lee D, et al. Among authors: pagire hs, pagire sh. J Med Chem. 2019 Jan 24;62(2):575-588. doi: 10.1021/acs.jmedchem.8b01168. Epub 2019 Jan 9. J Med Chem. 2019. PMID: 30623649
ENOblock inhibits the pathology of diet-induced obesity.
Cho H, Lee JH, Um J, Kim S, Kim Y, Kim WH, Kim YS, Pagire HS, Ahn JH, Ahn Y, Chang YT, Jung DW, Williams DR. Cho H, et al. Among authors: pagire hs. Sci Rep. 2019 Jan 24;9(1):493. doi: 10.1038/s41598-018-36715-3. Sci Rep. 2019. PMID: 30679508 Free PMC article.
Correction to Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases.
Lee D, Pagire HS, Pagire SH, Bae EJ, Dighe M, Kim M, Lee KM, Jang YK, Jaladi AK, Jung KY, Yoo EK, Gim HE, Lee S, Choi WI, Chi YI, Song JS, Bae MA, Jeon YH, Lee GH, Liu KH, Lee T, Park S, Jeon JH, Lee IK, Ahn JH. Lee D, et al. Among authors: pagire hs, pagire sh. J Med Chem. 2019 Mar 14;62(5):2849. doi: 10.1021/acs.jmedchem.9b00249. Epub 2019 Feb 27. J Med Chem. 2019. PMID: 30811938 No abstract available.
20 results