Paganetti P - Search Results

1

Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns.

Pérez-Berlanga M, Wiersma VI, Zbinden A, De Vos L, Wagner U, Foglieni C, Mallona I, Betz KM, Cléry A, Weber J, Guo Z, Rigort R, de Rossi P, Manglunia R, Tantardini E, Sahadevan S, Stach O, Hruska-Plochan M, Allain FH, Paganetti P, Polymenidou M. Pérez-Berlanga M, et al. Among authors: paganetti p. EMBO J. 2023 Sep 4;42(17):e111719. doi: 10.15252/embj.2022111719. Epub 2023 Jul 11. EMBO J. 2023. PMID: 37431963 Free PMC article.

2

Inducible mutant huntingtin expression in HN10 cells reproduces Huntington's disease-like neuronal dysfunction.

Weiss A, Roscic A, Paganetti P. Weiss A, et al. Among authors: paganetti p. Mol Neurodegener. 2009 Feb 9;4:11. doi: 10.1186/1750-1326-4-11. Mol Neurodegener. 2009. PMID: 19203385 Free PMC article.

3

Detection of a soluble form of BACE-1 in human cerebrospinal fluid by a sensitive activity assay.

Verheijen JH, Huisman LG, van Lent N, Neumann U, Paganetti P, Hack CE, Bouwman F, Lindeman J, Bollen EL, Hanemaaijer R. Verheijen JH, et al. Among authors: paganetti p. Clin Chem. 2006 Jun;52(6):1168-74. doi: 10.1373/clinchem.2006.066720. Epub 2006 Apr 13. Clin Chem. 2006. PMID: 16614000

4

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.

Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret JM, Paganetti P, Walsh DM, Mathews PM, Ghiso J, Staufenbiel M, Walker LC, Jucker M. Meyer-Luehmann M, et al. Among authors: paganetti p. Science. 2006 Sep 22;313(5794):1781-4. doi: 10.1126/science.1131864. Science. 2006. PMID: 16990547

5

Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER.

Molinari M, Galli C, Piccaluga V, Pieren M, Paganetti P. Molinari M, et al. Among authors: paganetti p. J Cell Biol. 2002 Jul 22;158(2):247-57. doi: 10.1083/jcb.200204122. Epub 2002 Jul 15. J Cell Biol. 2002. PMID: 12119363 Free PMC article.

6

A splice variant of beta-secretase deficient in the amyloidogenic processing of the amyloid precursor protein.

Bodendorf U, Fischer F, Bodian D, Multhaup G, Paganetti P. Bodendorf U, et al. Among authors: paganetti p. J Biol Chem. 2001 Apr 13;276(15):12019-23. doi: 10.1074/jbc.M008861200. Epub 2001 Jan 10. J Biol Chem. 2001. PMID: 11152683 Free article.

7

Development of a method for the high-throughput quantification of cellular proteins.

Paganetti P, Weiss A, Trapp M, Hammerl I, Bleckmann D, Bodner RA, Coven-Easter S, Housman DE, Parker CN. Paganetti P, et al. Chembiochem. 2009 Jul 6;10(10):1678-88. doi: 10.1002/cbic.200900131. Chembiochem. 2009. PMID: 19492395

8

Distinct processing of endogenous and overexpressed recombinant presenilin 1.

Baumann K, Paganetti PA, Sturchler-Pierrat C, Wong C, Hartmann H, Cescato R, Frey P, Yankner BA, Sommer B, Staufenbiel M. Baumann K, et al. Among authors: paganetti pa. Neurobiol Aging. 1997 Mar-Apr;18(2):181-9. doi: 10.1016/s0197-4580(97)00004-3. Neurobiol Aging. 1997. PMID: 9258895

9

Increased generation of alternatively cleaved beta-amyloid peptides in cells expressing mutants of the amyloid precursor protein defective in endocytosis.

Cescato R, Dumermuth E, Spiess M, Paganetti PA. Cescato R, et al. Among authors: paganetti pa. J Neurochem. 2000 Mar;74(3):1131-9. doi: 10.1046/j.1471-4159.2000.741131.x. J Neurochem. 2000. PMID: 10693945 Free article.

10

Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors.

Machauer R, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Neumann U, Paganetti P. Machauer R, et al. Among authors: paganetti p. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1361-5. doi: 10.1016/j.bmcl.2009.01.036. Epub 2009 Jan 19. Bioorg Med Chem Lett. 2009. PMID: 19195886

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