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Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer.
Proc Natl Acad Sci U S A. 2022 Feb 1;119(5):e2117754119. doi: 10.1073/pnas.2117754119.
Proc Natl Acad Sci U S A. 2022.
PMID: 35082152
Free PMC article.
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
Sánchez-Rivera FJ, Diaz BJ, Kastenhuber ER, Schmidt H, Katti A, Kennedy M, Tem V, Ho YJ, Leibold J, Paffenholz SV, Barriga FM, Chu K, Goswami S, Wuest AN, Simon JM, Tsanov KM, Chakravarty D, Zhang H, Leslie CS, Lowe SW, Dow LE.
Sánchez-Rivera FJ, et al. Among authors: paffenholz sv.
Nat Biotechnol. 2022 Jun;40(6):862-873. doi: 10.1038/s41587-021-01172-3. Epub 2022 Feb 14.
Nat Biotechnol. 2022.
PMID: 35165384
Free PMC article.
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Safety and activity of selinexor in patients with myelodysplastic syndromes or oligoblastic acute myeloid leukaemia refractory to hypomethylating agents: a single-centre, single-arm, phase 2 trial.
Taylor J, Mi X, Penson AV, Paffenholz SV, Alvarez K, Sigler A, Chung SS, Rampal RK, Park JH, Stein EM, Tallman MS, Sen F, Gönen M, Abdel-Wahab O, Klimek VM.
Taylor J, et al. Among authors: paffenholz sv.
Lancet Haematol. 2020 Aug;7(8):e566-e574. doi: 10.1016/S2352-3026(20)30209-X.
Lancet Haematol. 2020.
PMID: 32735836
Free PMC article.
Clinical Trial.
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Perception of the 2020 SARS-CoV-2 pandemic among medical professionals in Germany: results from a nationwide online survey.
Paffenholz P, Peine A, Hellmich M, Paffenholz SV, Martin L, Luedde M, Haverkamp M, Roderburg C, Marx G, Heidenreich A, Trautwein C, Luedde T, Loosen SH.
Paffenholz P, et al. Among authors: paffenholz sv.
Emerg Microbes Infect. 2020 Dec;9(1):1590-1599. doi: 10.1080/22221751.2020.1785951.
Emerg Microbes Infect. 2020.
PMID: 32573350
Free PMC article.
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Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Bogeska R, Mikecin AM, Kaschutnig P, Fawaz M, Büchler-Schäff M, Le D, Ganuza M, Vollmer A, Paffenholz SV, Asada N, Rodriguez-Correa E, Frauhammer F, Buettner F, Ball M, Knoch J, Stäble S, Walter D, Petri A, Carreño-Gonzalez MJ, Wagner V, Brors B, Haas S, Lipka DB, Essers MAG, Weru V, Holland-Letz T, Mallm JP, Rippe K, Krämer S, Schlesner M, McKinney Freeman S, Florian MC, King KY, Frenette PS, Rieger MA, Milsom MD.
Bogeska R, et al. Among authors: paffenholz sv.
Cell Stem Cell. 2022 Aug 4;29(8):1273-1284.e8. doi: 10.1016/j.stem.2022.06.012. Epub 2022 Jul 19.
Cell Stem Cell. 2022.
PMID: 35858618
Free PMC article.
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Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations.
Guarnerio J, Bezzi M, Jeong JC, Paffenholz SV, Berry K, Naldini MM, Lo-Coco F, Tay Y, Beck AH, Pandolfi PP.
Guarnerio J, et al. Among authors: paffenholz sv.
Cell. 2016 Aug 11;166(4):1055-1056. doi: 10.1016/j.cell.2016.07.035.
Cell. 2016.
PMID: 27518567
Free article.
No abstract available.
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Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations.
Guarnerio J, Bezzi M, Jeong JC, Paffenholz SV, Berry K, Naldini MM, Lo-Coco F, Tay Y, Beck AH, Pandolfi PP.
Guarnerio J, et al. Among authors: paffenholz sv.
Cell. 2016 Apr 7;165(2):289-302. doi: 10.1016/j.cell.2016.03.020. Epub 2016 Mar 31.
Cell. 2016.
PMID: 27040497
Free article.
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The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations.
Diederichs S, Bartsch L, Berkmann JC, Fröse K, Heitmann J, Hoppe C, Iggena D, Jazmati D, Karschnia P, Linsenmeier M, Maulhardt T, Möhrmann L, Morstein J, Paffenholz SV, Röpenack P, Rückert T, Sandig L, Schell M, Steinmann A, Voss G, Wasmuth J, Weinberger ME, Wullenkord R.
Diederichs S, et al. Among authors: paffenholz sv.
EMBO Mol Med. 2016 May 2;8(5):442-57. doi: 10.15252/emmm.201506055. Print 2016 May.
EMBO Mol Med. 2016.
PMID: 26992833
Free PMC article.
Review.
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