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Reducing gut microbiome-driven adipose tissue inflammation alleviates metabolic syndrome.
Newman NK, Zhang Y, Padiadpu J, Miranda CL, Magana AA, Wong CP, Hioki KA, Pederson JW, Li Z, Gurung M, Bruce AM, Brown K, Bobe G, Sharpton TJ, Shulzhenko N, Maier CS, Stevens JF, Gombart AF, Morgun A. Newman NK, et al. Among authors: padiadpu j. Microbiome. 2023 Sep 21;11(1):208. doi: 10.1186/s40168-023-01637-4. Microbiome. 2023. PMID: 37735685 Free PMC article.
Microbiota and adipocyte mitochondrial damage in type 2 diabetes are linked by Mmp12+ macrophages.
Li Z, Gurung M, Rodrigues RR, Padiadpu J, Newman NK, Manes NP, Pederson JW, Greer RL, Vasquez-Perez S, You H, Hioki KA, Moulton Z, Fel A, De Nardo D, Dzutsev AK, Nita-Lazar A, Trinchieri G, Shulzhenko N, Morgun A. Li Z, et al. Among authors: padiadpu j. J Exp Med. 2022 Jul 4;219(7):e20220017. doi: 10.1084/jem.20220017. Epub 2022 Jun 3. J Exp Med. 2022. PMID: 35657352 Free PMC article.
Transkingdom Network Analysis (TkNA): a systems framework for inferring causal factors underlying host-microbiota and other multi-omic interactions.
Newman NK, Macovsky M, Rodrigues RR, Bruce AM, Pederson JW, Patil SS, Padiadpu J, Dzutsev AK, Shulzhenko N, Trinchieri G, Brown K, Morgun A. Newman NK, et al. Among authors: padiadpu j. bioRxiv [Preprint]. 2023 Mar 29:2023.02.22.529449. doi: 10.1101/2023.02.22.529449. bioRxiv. 2023. PMID: 36865280 Free PMC article. Updated. Preprint.
Multi-omic network analysis identified betacellulin as a novel target of omega-3 fatty acid attenuation of western diet-induced nonalcoholic steatohepatitis.
Padiadpu J, Garcia-Jaramillo M, Newman NK, Pederson JW, Rodrigues R, Li Z, Singh S, Monnier P, Trinchieri G, Brown K, Dzutsev AK, Shulzhenko N, Jump DB, Morgun A. Padiadpu J, et al. EMBO Mol Med. 2023 Nov 8;15(11):e18367. doi: 10.15252/emmm.202318367. Epub 2023 Oct 20. EMBO Mol Med. 2023. PMID: 37859621 Free PMC article.
Intestinal IL-22RA1 signaling regulates intrinsic and systemic lipid and glucose metabolism to alleviate obesity-associated disorders.
Gaudino SJ, Singh A, Huang H, Padiadpu J, Jean-Pierre M, Kempen C, Bahadur T, Shiomitsu K, Blumberg R, Shroyer KR, Beyaz S, Shulzhenko N, Morgun A, Kumar P. Gaudino SJ, et al. Among authors: padiadpu j. Nat Commun. 2024 Feb 21;15(1):1597. doi: 10.1038/s41467-024-45568-6. Nat Commun. 2024. PMID: 38383607 Free PMC article.
Transkingdom Network Analysis (TkNA): a systems framework for inferring causal factors underlying host-microbiota and other multi-omic interactions.
Newman NK, Macovsky MS, Rodrigues RR, Bruce AM, Pederson JW, Padiadpu J, Shan J, Williams J, Patil SS, Dzutsev AK, Shulzhenko N, Trinchieri G, Brown K, Morgun A. Newman NK, et al. Among authors: padiadpu j. Nat Protoc. 2024 Mar 12. doi: 10.1038/s41596-024-00960-w. Online ahead of print. Nat Protoc. 2024. PMID: 38472495 Review.
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