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Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy.
Acta Pharmacol Sin. 2010 Sep;31(9):1181-8. doi: 10.1038/aps.2010.106. Epub 2010 Aug 9.
Acta Pharmacol Sin. 2010.
PMID: 20694025
Free PMC article.
Review.
Monoclonal antibody (mAb)-induced down-regulation of RON receptor tyrosine kinase diminishes tumorigenic activities of colon cancer cells.
Li Z, Yao H, Guin S, Padhye SS, Zhou YQ, Wang MH.
Li Z, et al. Among authors: padhye ss.
Int J Oncol. 2010 Aug;37(2):473-82. doi: 10.3892/ijo_00000696.
Int J Oncol. 2010.
PMID: 20596675
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Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein.
Ma Q, Guin S, Padhye SS, Zhou YQ, Zhang RW, Wang MH.
Ma Q, et al. Among authors: padhye ss.
Mol Cancer. 2011 May 28;10:66. doi: 10.1186/1476-4598-10-66.
Mol Cancer. 2011.
PMID: 21619683
Free PMC article.
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The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells.
Yao HP, Zhou YQ, Ma Q, Guin S, Padhye SS, Zhang RW, Wang MH.
Yao HP, et al. Among authors: padhye ss.
Mol Cancer. 2011 Jul 12;10:82. doi: 10.1186/1476-4598-10-82.
Mol Cancer. 2011.
PMID: 21749705
Free PMC article.
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Sustained expression of the RON receptor tyrosine kinase by pancreatic cancer stem cells as a potential targeting moiety for antibody-directed chemotherapeutics.
Padhye SS, Guin S, Yao HP, Zhou YQ, Zhang R, Wang MH.
Padhye SS, et al.
Mol Pharm. 2011 Dec 5;8(6):2310-9. doi: 10.1021/mp200193u. Epub 2011 Nov 1.
Mol Pharm. 2011.
PMID: 22014215
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Inhibition of MSP-RON signaling pathway in cancer cells by a novel soluble form of RON comprising the entire sema sequence.
Ma Q, Zhang K, Yao HP, Zhou YQ, Padhye S, Wang MH.
Ma Q, et al.
Int J Oncol. 2010 Jun;36(6):1551-61. doi: 10.3892/ijo_00000642.
Int J Oncol. 2010.
PMID: 20428780
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Targeting acute hypoxic cancer cells by doxorubicin-immunoliposomes directed by monoclonal antibodies specific to RON receptor tyrosine kinase.
Guin S, Ma Q, Padhye S, Zhou YQ, Yao HP, Wang MH.
Guin S, et al.
Cancer Chemother Pharmacol. 2011 May;67(5):1073-83. doi: 10.1007/s00280-010-1408-8. Epub 2010 Jul 25.
Cancer Chemother Pharmacol. 2011.
PMID: 20658288
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