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PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma.
Shin YJ, Sa JK, Lee Y, Kim D, Chang N, Cho HJ, Son M, Oh MYT, Shin K, Lee JK, Park J, Jo YK, Kim M, Paddison PJ, Tergaonkar V, Lee J, Nam DH. Shin YJ, et al. Among authors: paddison pj. J Exp Med. 2019 May 6;216(5):1120-1134. doi: 10.1084/jem.20172170. Epub 2019 Mar 21. J Exp Med. 2019. PMID: 30898893 Free PMC article.
Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells.
Ding Y, Hubert CG, Herman J, Corrin P, Toledo CM, Skutt-Kakaria K, Vazquez J, Basom R, Zhang B, Risler JK, Pollard SM, Nam DH, Delrow JJ, Zhu J, Lee J, DeLuca J, Olson JM, Paddison PJ. Ding Y, et al. Among authors: paddison pj. Cancer Discov. 2013 Feb;3(2):198-211. doi: 10.1158/2159-8290.CD-12-0353. Epub 2012 Nov 15. Cancer Discov. 2013. PMID: 23154965 Free PMC article.
Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A.
Hubert CG, Bradley RK, Ding Y, Toledo CM, Herman J, Skutt-Kakaria K, Girard EJ, Davison J, Berndt J, Corrin P, Hardcastle J, Basom R, Delrow JJ, Webb T, Pollard SM, Lee J, Olson JM, Paddison PJ. Hubert CG, et al. Among authors: paddison pj. Genes Dev. 2013 May 1;27(9):1032-45. doi: 10.1101/gad.212548.112. Genes Dev. 2013. PMID: 23651857 Free PMC article.
Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.
Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H, Davison J, Zhang Q, Hardcastle J, Aronow BJ, Plaisier CL, Baliga NS, Moffat J, Lin Q, Li XN, Nam DH, Lee J, Pollard SM, Zhu J, Delrow JJ, Clurman BE, Olson JM, Paddison PJ. Toledo CM, et al. Among authors: paddison pj. Cell Rep. 2015 Dec 22;13(11):2425-2439. doi: 10.1016/j.celrep.2015.11.021. Epub 2015 Dec 7. Cell Rep. 2015. PMID: 26673326 Free PMC article.
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN. Miller TE, et al. Among authors: paddison pj. Nature. 2017 Jul 20;547(7663):355-359. doi: 10.1038/nature23000. Epub 2017 Jul 5. Nature. 2017. PMID: 28678782 Free PMC article.
62 results