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SARS-CoV-2 Omicron variant emerged under immune selection.
Tan CW, Chia WN, Zhu F, Young BE, Chantasrisawad N, Hwa SH, Yeoh AY, Lim BL, Yap WC, Pada SKMS, Tan SY, Jantarabenjakul W, Toh LK, Chen S, Zhang J, Mah YY, Chen VC, Chen MI, Wacharapluesadee S, Sigal A, Putcharoen O, Lye DC, Wang LF. Tan CW, et al. Among authors: pada skms. Nat Microbiol. 2022 Nov;7(11):1756-1761. doi: 10.1038/s41564-022-01246-1. Epub 2022 Oct 4. Nat Microbiol. 2022. PMID: 36195753
High Yield of HIV Testing in Dengue-Like Febrile Illness in Singapore.
Verrall AJ, Lye DC, Pada S, Smitasin N, Lee CK, Khoo MJ, Koay ES, Leo YS, Fisher DA, Archuleta S. Verrall AJ, et al. Open Forum Infect Dis. 2018 Jul 13;5(8):ofy171. doi: 10.1093/ofid/ofy171. eCollection 2018 Aug. Open Forum Infect Dis. 2018. PMID: 30151405 Free PMC article.
Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2.
Su YCF, Anderson DE, Young BE, Linster M, Zhu F, Jayakumar J, Zhuang Y, Kalimuddin S, Low JGH, Tan CW, Chia WN, Mak TM, Octavia S, Chavatte JM, Lee RTC, Pada S, Tan SY, Sun L, Yan GZ, Maurer-Stroh S, Mendenhall IH, Leo YS, Lye DC, Wang LF, Smith GJD. Su YCF, et al. mBio. 2020 Jul 21;11(4):e01610-20. doi: 10.1128/mBio.01610-20. mBio. 2020. PMID: 32694143 Free PMC article.
Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity.
Amrun SN, Lee CY, Lee B, Fong SW, Young BE, Chee RS, Yeo NK, Torres-Ruesta A, Carissimo G, Poh CM, Chang ZW, Tay MZ, Chan YH, Chen MI, Low JG, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Leo YS, Lye DC, Renia L, Ng LFP. Amrun SN, et al. EBioMedicine. 2020 Aug;58:102911. doi: 10.1016/j.ebiom.2020.102911. Epub 2020 Jul 22. EBioMedicine. 2020. PMID: 32711254 Free PMC article.
Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study.
Young BE, Fong SW, Chan YH, Mak TM, Ang LW, Anderson DE, Lee CY, Amrun SN, Lee B, Goh YS, Su YCF, Wei WE, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Chen YYC, Barkham T, Lin RTP, Maurer-Stroh S, Leo YS, Wang LF, Renia L, Lee VJ, Smith GJD, Lye DC, Ng LFP. Young BE, et al. Lancet. 2020 Aug 29;396(10251):603-611. doi: 10.1016/S0140-6736(20)31757-8. Epub 2020 Aug 18. Lancet. 2020. PMID: 32822564 Free PMC article.
Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity.
Young BE, Ong SWX, Ng LFP, Anderson DE, Chia WN, Chia PY, Ang LW, Mak TM, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Fong SW, Chan YH, Tan CW, Lee B, Rötzschke O, Ding Y, Tambyah P, Low JGH, Cui L, Barkham T, Lin RTP, Leo YS, Renia L, Wang LF, Lye DC; Singapore 2019 Novel Coronavirus Outbreak Research Team. Young BE, et al. Clin Infect Dis. 2021 Nov 2;73(9):e2932-e2942. doi: 10.1093/cid/ciaa1280. Clin Infect Dis. 2021. PMID: 32856707 Free PMC article.
Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic individuals with COVID-19.
Goh YS, Chavatte JM, Lim Jieling A, Lee B, Hor PX, Amrun SN, Lee CY, Chee RS, Wang B, Lee CY, Ngoh EZX, Wang CI, Young BE, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Chen MI, Leo YS, Lye DC, Ng LFP, Lin RTP, Renia L. Goh YS, et al. Cell Rep Med. 2021 Feb 16;2(2):100193. doi: 10.1016/j.xcrm.2021.100193. Epub 2021 Jan 16. Cell Rep Med. 2021. PMID: 33495757 Free PMC article.
Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study.
Chia WN, Zhu F, Ong SWX, Young BE, Fong SW, Le Bert N, Tan CW, Tiu C, Zhang J, Tan SY, Pada S, Chan YH, Tham CYL, Kunasegaran K, Chen MI, Low JGH, Leo YS, Renia L, Bertoletti A, Ng LFP, Lye DC, Wang LF. Chia WN, et al. Lancet Microbe. 2021 Jun;2(6):e240-e249. doi: 10.1016/S2666-5247(21)00025-2. Epub 2021 Mar 23. Lancet Microbe. 2021. PMID: 33778792 Free PMC article.
Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: An observational study.
Young BE, Wei WE, Fong SW, Mak TM, Anderson DE, Chan YH, Pung R, Heng CS, Ang LW, Zheng AKE, Lee B, Kalimuddin S, Pada S, Tambyah PA, Parthasarathy P, Tan SY, Sun L, Smith GJ, Lin RTP, Leo YS, Renia L, Wang LF, Ng LF, Maurer-Stroh S, Lye DC, Lee VJ. Young BE, et al. EBioMedicine. 2021 Apr;66:103319. doi: 10.1016/j.ebiom.2021.103319. Epub 2021 Apr 8. EBioMedicine. 2021. PMID: 33840632 Free PMC article.
30 results