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Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain.
Tansley S, Uttam S, Ureña Guzmán A, Yaqubi M, Pacis A, Parisien M, Deamond H, Wong C, Rabau O, Brown N, Haglund L, Ouellet J, Santaguida C, Ribeiro-da-Silva A, Tahmasebi S, Prager-Khoutorsky M, Ragoussis J, Zhang J, Salter MW, Diatchenko L, Healy LM, Mogil JS, Khoutorsky A. Tansley S, et al. Among authors: pacis a. Nat Commun. 2022 Feb 11;13(1):843. doi: 10.1038/s41467-022-28473-8. Nat Commun. 2022. PMID: 35149686 Free PMC article.
Modeling High-Grade Serous Ovarian Carcinoma Using a Combination of In Vivo Fallopian Tube Electroporation and CRISPR-Cas9-Mediated Genome Editing.
Teng K, Ford MJ, Harwalkar K, Li Y, Pacis AS, Farnell D, Yamanaka N, Wang YC, Badescu D, Ton Nu TN, Ragoussis J, Huntsman DG, Arseneau J, Yamanaka Y. Teng K, et al. Cancer Res. 2021 Oct 15;81(20):5147-5160. doi: 10.1158/0008-5472.CAN-20-1518. Epub 2021 Jul 23. Cancer Res. 2021. PMID: 34301761 Free PMC article.
Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Meisel M, Hinterleitner R, Pacis A, Chen L, Earley ZM, Mayassi T, Pierre JF, Ernest JD, Galipeau HJ, Thuille N, Bouziat R, Buscarlet M, Ringus DL, Wang Y, Li Y, Dinh V, Kim SM, McDonald BD, Zurenski MA, Musch MW, Furtado GC, Lira SA, Baier G, Chang EB, Eren AM, Weber CR, Busque L, Godley LA, Verdú EF, Barreiro LB, Jabri B. Meisel M, et al. Among authors: pacis a. Nature. 2018 May;557(7706):580-584. doi: 10.1038/s41586-018-0125-z. Epub 2018 May 16. Nature. 2018. PMID: 29769727 Free PMC article.
Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation.
Lutz PE, Chay MA, Pacis A, Chen GG, Aouabed Z, Maffioletti E, Théroux JF, Grenier JC, Yang J, Aguirre M, Ernst C, Redensek A, van Kempen LC, Yalcin I, Kwan T, Mechawar N, Pastinen T, Turecki G. Lutz PE, et al. Among authors: pacis a. Nat Commun. 2021 Feb 18;12(1):1132. doi: 10.1038/s41467-021-21365-3. Nat Commun. 2021. PMID: 33602921 Free PMC article.
Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring.
Kuzmin E, Baker TM, Lesluyes T, Monlong J, Abe KT, Coelho PP, Schwartz M, Del Corpo J, Zou D, Morin G, Pacis A, Yang Y, Martinez C, Barber J, Kuasne H, Li R, Bourgey M, Fortier AM, Davison PG, Omeroglu A, Guiot MC, Morris Q, Kleinman CL, Huang S, Gingras AC, Ragoussis J, Bourque G, Van Loo P, Park M. Kuzmin E, et al. Among authors: pacis a. Cell Rep. 2024 Apr 23;43(4):113988. doi: 10.1016/j.celrep.2024.113988. Epub 2024 Mar 22. Cell Rep. 2024. PMID: 38517886 Free PMC article.
Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors.
Savage P, Pacis A, Kuasne H, Liu L, Lai D, Wan A, Dankner M, Martinez C, Muñoz-Ramos V, Pilon V, Monast A, Zhao H, Souleimanova M, Annis MG, Aguilar-Mahecha A, Lafleur J, Bertos NR, Asselah J, Bouganim N, Petrecca K, Siegel PM, Omeroglu A, Shah SP, Aparicio S, Basik M, Meterissian S, Park M. Savage P, et al. Among authors: pacis a. Commun Biol. 2020 Jun 16;3(1):310. doi: 10.1038/s42003-020-1042-x. Commun Biol. 2020. PMID: 32546838 Free PMC article.
Epigenetic variation impacts individual differences in the transcriptional response to influenza infection.
Aracena KA, Lin YL, Luo K, Pacis A, Gona S, Mu Z, Yotova V, Sindeaux R, Pramatarova A, Simon MM, Chen X, Groza C, Lougheed D, Gregoire R, Brownlee D, Boye C, Pique-Regi R, Li Y, He X, Bujold D, Pastinen T, Bourque G, Barreiro LB. Aracena KA, et al. Among authors: pacis a. Nat Genet. 2024 Mar;56(3):408-419. doi: 10.1038/s41588-024-01668-z. Epub 2024 Feb 29. Nat Genet. 2024. PMID: 38424460
37 results