Paci A - Search Results

1

Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.

Skarbek C, Lesueur LL, Chapuis H, Deroussent A, Pioche Durieu C, Daville A, Caron J, Rivard M, Martens T, Bertrand JR, Le Cam E, Vassal G, Couvreur P, Desmaele D, Paci A. Skarbek C, et al. Among authors: paci a. J Med Chem. 2015 Jan 22;58(2):705-17. doi: 10.1021/jm501224x. Epub 2014 Dec 23. J Med Chem. 2015. PMID: 25494842

2

Anodic oxidation of ifosfamide and cyclophosphamide: a biomimetic metabolism model of the oxazaphosphorinane anticancer drugs.

Paci A, Martens T, Royer J. Paci A, et al. Bioorg Med Chem Lett. 2001 May 21;11(10):1347-9. doi: 10.1016/s0960-894x(01)00218-9. Bioorg Med Chem Lett. 2001. PMID: 11392552

3

High-performance thin-layer chromatography with a derivatization procedure, a suitable method for the identification and the quantitation of busulfan in various pharmaceutical products.

Bouligand J, Paci A, Mercier L, Vassal G, Bourget P. Bouligand J, et al. Among authors: paci a. J Pharm Biomed Anal. 2004 Feb 18;34(3):525-30. doi: 10.1016/s0731-7085(03)00630-7. J Pharm Biomed Anal. 2004. PMID: 15127808

4

Liquid chromatography-mass spectrometry assay for quantitation of ifosfamide and its N-deschloroethylated metabolites in rat microsomal medium.

Storme T, Mercier L, Deroussent A, Re M, Martens T, Royer J, Bourget P, Vassal G, Paci A. Storme T, et al. Among authors: paci a. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jun 25;820(2):251-9. doi: 10.1016/j.jchromb.2005.03.023. Epub 2005 Apr 25. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 15899378

5

Quality control and stability study using HPTLC: applications to cyclophosphamide in various pharmaceutical products.

Bouligand J, Storme T, Laville I, Mercier L, Oberlin O, Vassal G, Bourget P, Paci A. Bouligand J, et al. Among authors: paci a. J Pharm Biomed Anal. 2005 Jun 1;38(1):180-5. doi: 10.1016/j.jpba.2004.12.001. J Pharm Biomed Anal. 2005. PMID: 15907638

6

Liquid chromatography-tandem mass spectrometry assay of reduced and oxidized glutathione and main precursors in mice liver.

Bouligand J, Deroussent A, Paci A, Morizet J, Vassal G. Bouligand J, et al. Among authors: paci a. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Feb 17;832(1):67-74. doi: 10.1016/j.jchromb.2005.12.037. Epub 2006 Jan 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16434243

7

Pharmacokinetics, metabolism, and routes of excretion of intravenous irofulven in patients with advanced solid tumors.

Paci A, Rezai K, Deroussent A, De Valeriola D, Re M, Weill S, Cvitkovic E, Kahatt C, Shah A, Waters S, Weems G, Vassal G, Lokiec F. Paci A, et al. Drug Metab Dispos. 2006 Nov;34(11):1918-26. doi: 10.1124/dmd.106.010512. Epub 2006 Aug 8. Drug Metab Dispos. 2006. PMID: 16896064 Clinical Trial.

8

Induction of glutathione synthesis explains pharmacodynamics of high-dose busulfan in mice and highlights putative mechanisms of drug interaction.

Bouligand J, Deroussent A, Simonnard N, Opolon P, Morizet J, Connault E, Daudigeos E, Re M, Paci A, Vassal G. Bouligand J, et al. Among authors: paci a. Drug Metab Dispos. 2007 Feb;35(2):306-14. doi: 10.1124/dmd.106.012880. Epub 2006 Nov 28. Drug Metab Dispos. 2007. PMID: 17132762

9

Synthesis and biological evaluation of two glycerolipidic prodrugs of didanosine for direct lymphatic delivery against HIV.

Lalanne M, Paci A, Andrieux K, Dereuddre-Bosquet N, Clayette P, Deroussent A, Ré M, Vassal G, Couvreur P, Desmaële D. Lalanne M, et al. Among authors: paci a. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2237-40. doi: 10.1016/j.bmcl.2007.01.062. Epub 2007 Jan 25. Bioorg Med Chem Lett. 2007. PMID: 17276686

10

Liposomal formulation of a glycerolipidic prodrug for lymphatic delivery of didanosine via oral route.

Lalanne M, Andrieux K, Paci A, Besnard M, Ré M, Bourgaux C, Ollivon M, Desmaele D, Couvreur P. Lalanne M, et al. Among authors: paci a. Int J Pharm. 2007 Nov 1;344(1-2):62-70. doi: 10.1016/j.ijpharm.2007.05.064. Epub 2007 Jun 3. Int J Pharm. 2007. PMID: 17616448

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