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Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2-SP1-SAT1 axis.
Murthy D, Attri KS, Shukla SK, Thakur R, Chaika NV, He C, Wang D, Jha K, Dasgupta A, King RJ, Mulder SE, Souchek J, Gebregiworgis T, Rai V, Patel R, Hu T, Rana S, Kollala SS, Pacheco C, Grandgenett PM, Yu F, Kumar V, Lazenby AJ, Black AR, Ulhannan S, Jain A, Edil BH, Klinkebiel DL, Powers R, Natarajan A, Hollingsworth MA, Mehla K, Ly Q, Chaudhary S, Hwang RF, Wellen KE, Singh PK. Murthy D, et al. Among authors: pacheco c. Nat Cell Biol. 2024 Apr;26(4):613-627. doi: 10.1038/s41556-024-01372-4. Epub 2024 Mar 1. Nat Cell Biol. 2024. PMID: 38429478 Free PMC article.
SIRT1-NOX4 signaling axis regulates cancer cachexia.
Dasgupta A, Shukla SK, Vernucci E, King RJ, Abrego J, Mulder SE, Mullen NJ, Graves G, Buettner K, Thakur R, Murthy D, Attri KS, Wang D, Chaika NV, Pacheco CG, Rai I, Engle DD, Grandgenett PM, Punsoni M, Reames BN, Teoh-Fitzgerald M, Oberley-Deegan R, Yu F, Klute KA, Hollingsworth MA, Zimmerman MC, Mehla K, Sadoshima J, Tuveson DA, Singh PK. Dasgupta A, et al. Among authors: pacheco cg. J Exp Med. 2020 Jul 6;217(7):e20190745. doi: 10.1084/jem.20190745. J Exp Med. 2020. PMID: 32441762 Free PMC article.
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.
Hu T, Shukla SK, Vernucci E, He C, Wang D, King RJ, Jha K, Siddhanta K, Mullen NJ, Attri KS, Murthy D, Chaika NV, Thakur R, Mulder SE, Pacheco CG, Fu X, High RR, Yu F, Lazenby A, Steegborn C, Lan P, Mehla K, Rotili D, Chaudhary S, Valente S, Tafani M, Mai A, Auwerx J, Verdin E, Tuveson D, Singh PK. Hu T, et al. Among authors: pacheco cg. Gastroenterology. 2021 Nov;161(5):1584-1600. doi: 10.1053/j.gastro.2021.06.045. Epub 2021 Jul 8. Gastroenterology. 2021. PMID: 34245764 Free PMC article.
CD73 induces GM-CSF/MDSC-mediated suppression of T cells to accelerate pancreatic cancer pathogenesis.
King RJ, Shukla SK, He C, Vernucci E, Thakur R, Attri KS, Dasgupta A, Chaika NV, Mulder SE, Abrego J, Murthy D, Gunda V, Pacheco CG, Grandgenett PM, Lazenby AJ, Hollingsworth MA, Yu F, Mehla K, Singh PK. King RJ, et al. Among authors: pacheco cg. Oncogene. 2022 Feb;41(7):971-982. doi: 10.1038/s41388-021-02132-6. Epub 2022 Jan 10. Oncogene. 2022. PMID: 35001076 Free PMC article.
Vitamin B6 Competition in the Tumor Microenvironment Hampers Antitumor Functions of NK Cells.
He C, Wang D, Shukla SK, Hu T, Thakur R, Fu X, King RJ, Kollala SS, Attri KS, Murthy D, Chaika NV, Fujii Y, Gonzalez D, Pacheco CG, Qiu Y, Singh PK, Locasale JW, Mehla K. He C, et al. Among authors: pacheco cg. Cancer Discov. 2024 Jan 12;14(1):176-193. doi: 10.1158/2159-8290.CD-23-0334. Cancer Discov. 2024. PMID: 37931287 Free PMC article.
Author Correction: Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2-SP1-SAT1 axis.
Murthy D, Attri KS, Shukla SK, Thakur R, Chaika NV, He C, Wang D, Jha K, Dasgupta A, King RJ, Mulder SE, Souchek J, Gebregiworgis T, Rai V, Patel R, Hu T, Rana S, Kollala SS, Pacheco C, Grandgenett PM, Yu F, Kumar V, Lazenby AJ, Black AR, Ulhannan S, Jain A, Edil BH, Klinkebiel DL, Powers R, Natarajan A, Hollingsworth MA, Mehla K, Ly Q, Chaudhary S, Hwang RF, Wellen KE, Singh PK. Murthy D, et al. Among authors: pacheco c. Nat Cell Biol. 2024 Apr 19. doi: 10.1038/s41556-024-01417-8. Online ahead of print. Nat Cell Biol. 2024. PMID: 38641662 No abstract available.
Standardized indolent systemic mastocytosis evaluations across a healthcare system: implications for screening accuracy.
McMurray JC, Pacheco CS, Schornack BJ, Sun X, Brunader JA, Scott AE, Ariza JS, Kou CJ, Costantino RC, Pittman LM, Adams KE, Waters AM, Pryor EM, Lyons JJ, Metcalfe D, Maric I, Boggs NA. McMurray JC, et al. Among authors: pacheco cs. Blood. 2024 Apr 18:blood.2023023347. doi: 10.1182/blood.2023023347. Online ahead of print. Blood. 2024. PMID: 38635793
Arterial stiffness assessment in coronary microvascular dysfunction and heart failure with preserved ejection fraction: An initial report from the WISE-CVD continuation study.
Rezaeian P, Shufelt CL, Wei J, Pacheco C, Cook-Wiens G, Berman D, Tamarappoo B, Thomson LE, Nelson MD, Anderson RD, Petersen J, Handberg EM, Pepine CJ, Merz CNB. Rezaeian P, et al. Among authors: pacheco c. Am Heart J Plus. 2024 Mar 31;41:100390. doi: 10.1016/j.ahjo.2024.100390. eCollection 2024 May. Am Heart J Plus. 2024. PMID: 38600957 Free PMC article.
472 results