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Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells.
Nat Commun. 2023 Jan 12;14(1):180. doi: 10.1038/s41467-023-35859-9.
Nat Commun. 2023.
PMID: 36635295
Free PMC article.
Protocol to study sufficiency of cis-regulatory elements in mouse embryonic stem cells using a CRISPR-mediated knockin approach.
Pachano T, Rada-Iglesias A.
Pachano T, et al.
STAR Protoc. 2022 Jun 21;3(3):101492. doi: 10.1016/j.xpro.2022.101492. eCollection 2022 Sep 16.
STAR Protoc. 2022.
PMID: 35769926
Free PMC article.
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Enhancer-gene specificity in development and disease.
Pachano T, Haro E, Rada-Iglesias A.
Pachano T, et al.
Development. 2022 Jun 1;149(11):dev186536. doi: 10.1242/dev.186536. Epub 2022 Jun 10.
Development. 2022.
PMID: 35686641
Free PMC article.
Review.
Item in Clipboard
The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo.
Crispatzu G, Rehimi R, Pachano T, Bleckwehl T, Cruz-Molina S, Xiao C, Mahabir E, Bazzi H, Rada-Iglesias A.
Crispatzu G, et al. Among authors: pachano t.
Nat Commun. 2021 Jul 16;12(1):4344. doi: 10.1038/s41467-021-24641-4.
Nat Commun. 2021.
PMID: 34272393
Free PMC article.
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Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness.
Pachano T, Sánchez-Gaya V, Ealo T, Mariner-Faulí M, Bleckwehl T, Asenjo HG, Respuela P, Cruz-Molina S, Muñoz-San Martín M, Haro E, van IJcken WFJ, Landeira D, Rada-Iglesias A.
Pachano T, et al.
Nat Genet. 2021 Jul;53(7):1036-1049. doi: 10.1038/s41588-021-00888-x. Epub 2021 Jun 28.
Nat Genet. 2021.
PMID: 34183853
Free PMC article.
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Polycomb proteins as organizers of 3D genome architecture in embryonic stem cells.
Pachano T, Crispatzu G, Rada-Iglesias A.
Pachano T, et al.
Brief Funct Genomics. 2019 Nov 19;18(6):358-366. doi: 10.1093/bfgp/elz022.
Brief Funct Genomics. 2019.
PMID: 31673701
Review.
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Epigenetics regulates transcription and pathogenesis in the parasite Trichomonas vaginalis.
Pachano T, Nievas YR, Lizarraga A, Johnson PJ, Strobl-Mazzulla PH, de Miguel N.
Pachano T, et al.
Cell Microbiol. 2017 Jun;19(6). doi: 10.1111/cmi.12716. Epub 2017 Jan 22.
Cell Microbiol. 2017.
PMID: 28054438
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