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In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies.
Ieranò C, Righelli D, D'Alterio C, Napolitano M, Portella L, Rea G, Auletta F, Santagata S, Trotta AM, Guardascione G, Liotti F, Prevete N, Maiolino P, Luciano A, Barbieri A, Di Mauro A, Roma C, Esposito Abate R, Tatangelo F, Pacelli R, Normanno N, Melillo RM, Scala S. Ieranò C, et al. Among authors: pacelli r. J Immunother Cancer. 2022 Mar;10(3):e004032. doi: 10.1136/jitc-2021-004032. J Immunother Cancer. 2022. PMID: 35246475 Free PMC article.
A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients.
D'Alterio C, Avallone A, Tatangelo F, Delrio P, Pecori B, Cella L, Pelella A, D'Armiento FP, Carlomagno C, Bianco F, Silvestro L, Pacelli R, Napolitano M, Iaffaioli RV, Scala S. D'Alterio C, et al. Among authors: pacelli r. Int J Cancer. 2014 Jul 15;135(2):379-90. doi: 10.1002/ijc.28689. Epub 2014 Jan 10. Int J Cancer. 2014. PMID: 24375277 Free article.
Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients.
Napolitano M, D'Alterio C, Cardone E, Trotta AM, Pecori B, Rega D, Pace U, Scala D, Scognamiglio G, Tatangelo F, Cacciapuoti C, Pacelli R, Delrio P, Scala S. Napolitano M, et al. Among authors: pacelli r. Oncotarget. 2015 Apr 10;6(10):8261-70. doi: 10.18632/oncotarget.3014. Oncotarget. 2015. PMID: 25823653 Free PMC article.
CXCR4-CXCL12-CXCR7, TLR2-TLR4, and PD-1/PD-L1 in colorectal cancer liver metastases from neoadjuvant-treated patients.
D'Alterio C, Nasti G, Polimeno M, Ottaiano A, Conson M, Circelli L, Botti G, Scognamiglio G, Santagata S, De Divitiis C, Nappi A, Napolitano M, Tatangelo F, Pacelli R, Izzo F, Vuttariello E, Botti G, Scala S. D'Alterio C, et al. Among authors: pacelli r. Oncoimmunology. 2016 Nov 29;5(12):e1254313. doi: 10.1080/2162402X.2016.1254313. eCollection 2016. Oncoimmunology. 2016. PMID: 28123896 Free PMC article.
Predictive immune biomarkers: an unattainable chimera?
Trotta AM, Pacelli R, Scala S. Trotta AM, et al. Among authors: pacelli r. Cell Mol Immunol. 2018 Aug;15(8):740-742. doi: 10.1038/cmi.2017.162. Epub 2018 Feb 5. Cell Mol Immunol. 2018. PMID: 29400708 Free PMC article. No abstract available.
Engineering of thermoresponsive gels as a fake metastatic niche.
Giarra S, Ierano C, Biondi M, Napolitano M, Campani V, Pacelli R, Scala S, De Rosa G, Mayol L. Giarra S, et al. Among authors: pacelli r. Carbohydr Polym. 2018 Jul 1;191:112-118. doi: 10.1016/j.carbpol.2018.03.016. Epub 2018 Mar 10. Carbohydr Polym. 2018. PMID: 29661298
113 results