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Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators.
Peltner LK, Gluthmann L, Börner F, Pace S, Hoffstetter RK, Kretzer C, Bilancia R, Pollastro F, Koeberle A, Appendino G, Rossi A, Newcomer ME, Gilbert NC, Werz O, Jordan PM. Peltner LK, et al. Among authors: pace s. Cell Chem Biol. 2023 Dec 21;30(12):1508-1524.e7. doi: 10.1016/j.chembiol.2023.08.001. Epub 2023 Aug 29. Cell Chem Biol. 2023. PMID: 37647900
Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution.
Jordan PM, Gerstmeier J, Pace S, Bilancia R, Rao Z, Börner F, Miek L, Gutiérrez-Gutiérrez Ó, Arakandy V, Rossi A, Ialenti A, González-Estévez C, Löffler B, Tuchscherr L, Serhan CN, Werz O. Jordan PM, et al. Among authors: pace s. Cell Rep. 2020 Oct 13;33(2):108247. doi: 10.1016/j.celrep.2020.108247. Cell Rep. 2020. PMID: 33053344 Free PMC article.
From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution.
Van Anh TT, Mostafa A, Rao Z, Pace S, Schwaiger S, Kretzer C, Temml V, Giesel C, Jordan PM, Bilancia R, Weinigel C, Rummler S, Waltenberger B, Hung T, Rossi A, Stuppner H, Werz O, Koeberle A. Van Anh TT, et al. Among authors: pace s. Acta Pharm Sin B. 2021 Jun;11(6):1629-1647. doi: 10.1016/j.apsb.2021.04.011. Epub 2021 Apr 20. Acta Pharm Sin B. 2021. PMID: 34221873 Free PMC article.
Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome.
Werner M, Jordan PM, Romp E, Czapka A, Rao Z, Kretzer C, Koeberle A, Garscha U, Pace S, Claesson HE, Serhan CN, Werz O, Gerstmeier J. Werner M, et al. Among authors: pace s. FASEB J. 2019 May;33(5):6140-6153. doi: 10.1096/fj.201802509R. Epub 2019 Feb 8. FASEB J. 2019. PMID: 30735438 Free PMC article.
., Czapka, A., Rao, Z., Kretzer, C., Koeberle, A., Garscha, U., Pace, S., Claesson, H.-E., Serhan, C. N., Werz, O., Gerstmeier, J. ...
., Czapka, A., Rao, Z., Kretzer, C., Koeberle, A., Garscha, U., Pace, S., Claesson, H.-E., Serhan, C. N., Werz, O., Gerstmeier …
354 results