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Hypothalamic Glucose Hypersensitivity-Induced Insulin Secretion in the Obese Zücker Rat Is Reversed by Central Ghrelin Treatment.
Carneiro L, Fenech C, Liénard F, Grall S, Abed B, Haydar J, Allard C, Desmoulins L, Paccoud R, Brindisi MC, Mouillot T, Brondel L, Fioramonti X, Pénicaud L, Jacquin-Piques A, Leloup C. Carneiro L, et al. Among authors: paccoud r. Antioxid Redox Signal. 2023 Mar 7. doi: 10.1089/ars.2022.0031. Online ahead of print. Antioxid Redox Signal. 2023. PMID: 36656675
The Tyrosine Phosphatase SHP2: A New Target for Insulin Resistance?
Saint-Laurent C, Mazeyrie L, Tajan M, Paccoud R, Castan-Laurell I, Valet P, Edouard T, Pradère JP, Dray C, Yart A. Saint-Laurent C, et al. Among authors: paccoud r. Biomedicines. 2022 Aug 31;10(9):2139. doi: 10.3390/biomedicines10092139. Biomedicines. 2022. PMID: 36140242 Free PMC article. Review.
Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor.
Personnaz J, Piccolo E, Dortignac A, Iacovoni JS, Mariette J, Rocher V, Polizzi A, Batut A, Deleruyelle S, Bourdens L, Delos O, Combes-Soia L, Paccoud R, Moreau E, Martins F, Clouaire T, Benhamed F, Montagner A, Wahli W, Schwabe RF, Yart A, Castan-Laurell I, Bertrand-Michel J, Burlet-Schiltz O, Postic C, Denechaud PD, Moro C, Legube G, Lee CH, Guillou H, Valet P, Dray C, Pradère JP. Personnaz J, et al. Among authors: paccoud r. Sci Adv. 2022 Mar 25;8(12):eabg9055. doi: 10.1126/sciadv.abg9055. Epub 2022 Mar 25. Sci Adv. 2022. PMID: 35333579 Free PMC article.
SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations.
Paccoud R, Saint-Laurent C, Piccolo E, Tajan M, Dortignac A, Pereira O, Le Gonidec S, Baba I, Gélineau A, Askia H, Branchereau M, Charpentier J, Personnaz J, Branka S, Auriau J, Deleruyelle S, Canouil M, Beton N, Salles JP, Tauber M, Weill J, Froguel P, Neel BG, Araki T, Heymes C, Burcelin R, Castan I, Valet P, Dray C, Gautier EL, Edouard T, Pradère JP, Yart A. Paccoud R, et al. Sci Transl Med. 2021 Apr 28;13(591):eabe2587. doi: 10.1126/scitranslmed.abe2587. Epub 2021 Apr 28. Sci Transl Med. 2021. PMID: 33910978
Macrophage-derived HMGB1 is dispensable for tissue fibrogenesis.
Personnaz J, Piccolo E, Branchereau M, Filliol A, Paccoud R, Moreau E, Calise D, Riant E, Gourdy P, Heymes C, Schwabe RF, Dray C, Valet P, Pradère JP. Personnaz J, et al. Among authors: paccoud r. FASEB Bioadv. 2019 Feb 12;1(4):227-245. doi: 10.1096/fba.2018-00035. eCollection 2019 Apr. FASEB Bioadv. 2019. PMID: 32123829 Free PMC article.
Mitochondrial Dynamin-Related Protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing.
Desmoulins L, Chrétien C, Paccoud R, Collins S, Cruciani-Guglielmacci C, Galinier A, Liénard F, Quinault A, Grall S, Allard C, Fenech C, Carneiro L, Mouillot T, Fournel A, Knauf C, Magnan C, Fioramonti X, Pénicaud L, Leloup C. Desmoulins L, et al. Among authors: paccoud r. Mol Metab. 2019 Feb;20:166-177. doi: 10.1016/j.molmet.2018.11.007. Epub 2018 Nov 27. Mol Metab. 2019. PMID: 30553770 Free PMC article.