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Human gene-engineered calreticulin mutant stem cells recapitulate MPN hallmarks and identify targetable vulnerabilities.
Foßelteder J, Pabst G, Sconocchia T, Schlacher A, Auinger L, Kashofer K, Beham-Schmid C, Trajanoski S, Waskow C, Schöll W, Sill H, Zebisch A, Wölfler A, Thomas D, Reinisch A. Foßelteder J, et al. Among authors: pabst g. Leukemia. 2023 Apr;37(4):843-853. doi: 10.1038/s41375-023-01848-6. Epub 2023 Feb 22. Leukemia. 2023. PMID: 36813992 Free PMC article.
Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi.
Jensen TI, Mikkelsen NS, Gao Z, Foßelteder J, Pabst G, Axelgaard E, Laustsen A, König S, Reinisch A, Bak RO. Jensen TI, et al. Among authors: pabst g. Genome Res. 2021 Nov;31(11):2120-2130. doi: 10.1101/gr.275607.121. Epub 2021 Aug 18. Genome Res. 2021. PMID: 34407984 Free PMC article.
Clinical implications of subclonal TP53 mutations in acute myeloid leukemia.
Prochazka KT, Pregartner G, Rücker FG, Heitzer E, Pabst G, Wölfler A, Zebisch A, Berghold A, Döhner K, Sill H. Prochazka KT, et al. Among authors: pabst g. Haematologica. 2019 Mar;104(3):516-523. doi: 10.3324/haematol.2018.205013. Epub 2018 Oct 11. Haematologica. 2019. PMID: 30309854 Free PMC article.
Eutectic Resolves Lysolipid Paradox in Thermoresponsive Liposomes.
Eckhardt D, Semeraro EF, Steigenberger J, Schnur J, Kalie L, Massing U, Pabst G, Heerklotz H. Eckhardt D, et al. Among authors: pabst g. Mol Pharm. 2024 Apr 1;21(4):1768-1776. doi: 10.1021/acs.molpharmaceut.3c01094. Epub 2024 Feb 21. Mol Pharm. 2024. PMID: 38381374
170 results