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A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology.
Marttinen M, Paananen J, Neme A, Mitra V, Takalo M, Natunen T, Paldanius KMA, Mäkinen P, Bremang M, Kurki MI, Rauramaa T, Leinonen V, Soininen H, Haapasalo A, Pike I, Hiltunen M. Marttinen M, et al. Among authors: paananen j. Neurobiol Dis. 2019 Apr;124:454-468. doi: 10.1016/j.nbd.2018.12.009. Epub 2018 Dec 15. Neurobiol Dis. 2019. PMID: 30557660 Free article.
Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus.
Huovinen J, Helisalmi S, Paananen J, Laiterä T, Kojoukhova M, Sutela A, Vanninen R, Laitinen M, Rauramaa T, Koivisto AM, Remes AM, Soininen H, Kurki M, Haapasalo A, Jääskeläinen JE, Hiltunen M, Leinonen V. Huovinen J, et al. Among authors: paananen j. J Alzheimers Dis. 2017;60(3):1077-1085. doi: 10.3233/JAD-170583. J Alzheimers Dis. 2017. PMID: 28984604
Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T, Takalo M, Kemppainen S, Leskelä S, Marttinen M, Kurkinen KMA, Pursiheimo JP, Sarajärvi T, Viswanathan J, Gabbouj S, Solje E, Tahvanainen E, Pirttimäki T, Kurki M, Paananen J, Rauramaa T, Miettinen P, Mäkinen P, Leinonen V, Soininen H, Airenne K, Tanzi RE, Tanila H, Haapasalo A, Hiltunen M. Natunen T, et al. Among authors: paananen j. Neurobiol Dis. 2016 Jan;85:187-205. doi: 10.1016/j.nbd.2015.11.005. Epub 2015 Nov 10. Neurobiol Dis. 2016. PMID: 26563932
SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.
Kurkinen KM, Marttinen M, Turner L, Natunen T, Mäkinen P, Haapalinna F, Sarajärvi T, Gabbouj S, Kurki M, Paananen J, Koivisto AM, Rauramaa T, Leinonen V, Tanila H, Soininen H, Lucas FR, Haapasalo A, Hiltunen M. Kurkinen KM, et al. Among authors: paananen j. J Cell Sci. 2016 Jun 1;129(11):2224-38. doi: 10.1242/jcs.185215. Epub 2016 Apr 15. J Cell Sci. 2016. PMID: 27084579
Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-β Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.
Laiterä T, Paananen J, Helisalmi S, Sarajärvi T, Huovinen J, Laitinen M, Rauramaa T, Alafuzoff I, Remes AM, Soininen H, Haapasalo A, Jääskeläinen JE, Leinonen V, Hiltunen M. Laiterä T, et al. Among authors: paananen j. J Alzheimers Dis. 2017;55(3):995-1003. doi: 10.3233/JAD-160554. J Alzheimers Dis. 2017. PMID: 27802227
TAFFEL: Independent Enrichment Analysis of gene sets.
Kurki MI, Paananen J, Storvik M, Ylä-Herttuala S, Jääskeläinen JE, von Und Zu Fraunberg M, Wong G, Pehkonen P. Kurki MI, et al. Among authors: paananen j. BMC Bioinformatics. 2011 May 19;12:171. doi: 10.1186/1471-2105-12-171. BMC Bioinformatics. 2011. PMID: 21592412 Free PMC article.
In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury-Lessons Learned.
Lipponen A, Natunen T, Hujo M, Ciszek R, Hämäläinen E, Tohka J, Hiltunen M, Paananen J, Poulsen D, Kansanen E, Ekolle Ndode-Ekane X, Levonen AL, Pitkänen A. Lipponen A, et al. Among authors: paananen j. Int J Mol Sci. 2019 Oct 29;20(21):5395. doi: 10.3390/ijms20215395. Int J Mol Sci. 2019. PMID: 31671916 Free PMC article.
85 results