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Lys-urea-Aad, Lys-urea-Cmc and Lys-urea-Cms as potential pharmacophores for the design of PSMA-targeted radioligands to reduce off-target uptake in kidneys and salivary glands.
Theranostics. 2023 Aug 15;13(13):4559-4573. doi: 10.7150/thno.87663. eCollection 2023.
Theranostics. 2023.
PMID: 37649602
Free PMC article.
What a difference a methylene makes: replacing Glu with Asp or Aad in the Lys-urea-Glu pharmacophore of PSMA-targeting radioligands to reduce kidney and salivary gland uptake.
Kuo HT, Lin KS, Zhang Z, Zhang C, Merkens H, Tan R, Roxin A, Uribe CF, Bénard F.
Kuo HT, et al.
Theranostics. 2022 Aug 21;12(14):6179-6188. doi: 10.7150/thno.76571. eCollection 2022.
Theranostics. 2022.
PMID: 36168623
Free PMC article.
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