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2021 2
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Parvalbumin interneuron loss mediates repeated anesthesia-induced memory deficits in mice.
Roque PS, Thörn Perez C, Hooshmandi M, Wong C, Eslamizade MJ, Heshmati S, Brown N, Sharma V, Lister KC, Goyon VM, Neagu-Lund L, Shen C, Daccache N, Sato H, Sato T, Mogil JS, Nader K, Gkogkas CG, Iordanova MD, Prager-Khoutorsky M, McBride HM, Lacaille JC, Wykes L, Schricker T, Khoutorsky A. Roque PS, et al. J Clin Invest. 2023 Jan 17;133(2):e159344. doi: 10.1172/JCI159344. J Clin Invest. 2023. PMID: 36394958 Free PMC article.
mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation.
Wong C, Barkai O, Wang F, Perez CT, Lev S, Cai W, Tansley S, Yousefpour N, Hooshmandi M, Lister KC, Latif M, Cuello AC, Prager-Khoutorsky M, Mogil JS, Séguéla P, De Koninck Y, Ribeiro-da-Silva A, Binshtok AM, Khoutorsky A. Wong C, et al. J Clin Invest. 2022 Aug 1;132(15):e152635. doi: 10.1172/JCI152635. J Clin Invest. 2022. PMID: 35579957 Free PMC article.
Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain.
Tansley S, Uttam S, Ureña Guzmán A, Yaqubi M, Pacis A, Parisien M, Deamond H, Wong C, Rabau O, Brown N, Haglund L, Ouellet J, Santaguida C, Ribeiro-da-Silva A, Tahmasebi S, Prager-Khoutorsky M, Ragoussis J, Zhang J, Salter MW, Diatchenko L, Healy LM, Mogil JS, Khoutorsky A. Tansley S, et al. Nat Commun. 2022 Feb 11;13(1):843. doi: 10.1038/s41467-022-28473-8. Nat Commun. 2022. PMID: 35149686 Free PMC article.
4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors.
Hooshmandi M, Truong VT, Fields E, Thomas RE, Wong C, Sharma V, Gantois I, Soriano Roque P, Chalkiadaki K, Wu N, Chakraborty A, Tahmasebi S, Prager-Khoutorsky M, Sonenberg N, Suvrathan A, Watt AJ, Gkogkas CG, Khoutorsky A. Hooshmandi M, et al. Cell Rep. 2021 Apr 27;35(4):109036. doi: 10.1016/j.celrep.2021.109036. Cell Rep. 2021. PMID: 33910008 Free article.
4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold.
Sharma V, Sood R, Lou D, Hung TY, Lévesque M, Han Y, Levett JY, Wang P, Murthy S, Tansley S, Wang S, Siddiqui N, Tahmasebi S, Rosenblum K, Avoli M, Lacaille JC, Sonenberg N, Khoutorsky A. Sharma V, et al. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2025522118. doi: 10.1073/pnas.2025522118. Proc Natl Acad Sci U S A. 2021. PMID: 33876772 Free PMC article.