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Year | Number of Results |
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2018 | 1 |
2019 | 1 |
2020 | 1 |
2021 | 3 |
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A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases.
Stem Cell Reports. 2023 Dec 12;18(12):2386-2399. doi: 10.1016/j.stemcr.2023.10.014. Epub 2023 Nov 16.
Stem Cell Reports. 2023.
PMID: 37977146
Free PMC article.
Identification of an Altered Matrix Signature in Kidney Aging and Disease.
Randles MJ, Lausecker F, Kong Q, Suleiman H, Reid G, Kolatsi-Joannou M, Davenport B, Tian P, Falcone S, Potter P, Van Agtmael T, Norman JT, Long DA, Humphries MJ, Miner JH, Lennon R.
Randles MJ, et al.
J Am Soc Nephrol. 2021 Jul;32(7):1713-1732. doi: 10.1681/ASN.2020101442. Epub 2021 May 28.
J Am Soc Nephrol. 2021.
PMID: 34049963
Free PMC article.
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Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease.
Pokhilko A, Brezzo G, Handunnetthi L, Heilig R, Lennon R, Smith C, Allan SM, Granata A, Sinha S, Wang T, Markus HS, Naba A, Fischer R, Van Agtmael T, Horsburgh K, Cader MZ.
Pokhilko A, et al.
J Cereb Blood Flow Metab. 2021 Sep;41(9):2423-2438. doi: 10.1177/0271678X211004307. Epub 2021 Mar 17.
J Cereb Blood Flow Metab. 2021.
PMID: 33730931
Free PMC article.
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Basement membrane stiffness determines metastases formation.
Reuten R, Zendehroud S, Nicolau M, Fleischhauer L, Laitala A, Kiderlen S, Nikodemus D, Wullkopf L, Nielsen SR, McNeilly S, Prein C, Rafaeva M, Schoof EM, Furtwängler B, Porse BT, Kim H, Won KJ, Sudhop S, Zornhagen KW, Suhr F, Maniati E, Pearce OMT, Koch M, Oddershede LB, Van Agtmael T, Madsen CD, Mayorca-Guiliani AE, Bloch W, Netz RR, Clausen-Schaumann H, Erler JT.
Reuten R, et al.
Nat Mater. 2021 Jun;20(6):892-903. doi: 10.1038/s41563-020-00894-0. Epub 2021 Jan 25.
Nat Mater. 2021.
PMID: 33495631
Free article.
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Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts.
Ngandu Mpoyi E, Cantini M, Sin YY, Fleming L, Zhou DW, Costell M, Lu Y, Kadler K, García AJ, Van Agtmael T, Salmeron-Sanchez M.
Ngandu Mpoyi E, et al.
Biomaterials. 2020 Sep;252:120090. doi: 10.1016/j.biomaterials.2020.120090. Epub 2020 May 3.
Biomaterials. 2020.
PMID: 32413593
Free PMC article.
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4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease.
Jones FE, Murray LS, McNeilly S, Dean A, Aman A, Lu Y, Nikolova N, Malomgré R, Horsburgh K, Holmes WM, Kadler KE, Van Agtmael T.
Jones FE, et al.
Hum Mol Genet. 2019 Feb 15;28(4):628-638. doi: 10.1093/hmg/ddy369.
Hum Mol Genet. 2019.
PMID: 30351356
Free PMC article.
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Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.
Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, Cader MZ, Carare RO, Davis JB, Duncombe J, Farr TD, Fowler JH, Goense J, Granata A, Hall CN, Hainsworth AH, Harvey A, Hawkes CA, Joutel A, Kalaria RN, Kehoe PG, Lawrence CB, Lockhart A, Love S, Macleod MR, Macrae IM, Markus HS, McCabe C, McColl BW, Meakin PJ, Miller A, Nedergaard M, O'Sullivan M, Quinn TJ, Rajani R, Saksida LM, Smith C, Smith KJ, Touyz RM, Trueman RC, Wang T, Williams A, Williams SCR, Work LM.
Horsburgh K, et al.
Clin Sci (Lond). 2018 Apr 30;132(8):851-868. doi: 10.1042/CS20171620. Print 2018 Apr 30.
Clin Sci (Lond). 2018.
PMID: 29712883
Free PMC article.
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