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Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform.
Br J Pharmacol. 2018 Mar;175(6):938-952. doi: 10.1111/bph.14136. Epub 2018 Feb 5.
Br J Pharmacol. 2018.
PMID: 29278865
Free PMC article.
Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance.
Rode B, Shi J, Endesh N, Drinkhill MJ, Webster PJ, Lotteau SJ, Bailey MA, Yuldasheva NY, Ludlow MJ, Cubbon RM, Li J, Futers TS, Morley L, Gaunt HJ, Marszalek K, Viswambharan H, Cuthbertson K, Baxter PD, Foster R, Sukumar P, Weightman A, Calaghan SC, Wheatcroft SB, Kearney MT, Beech DJ.
Rode B, et al.
Nat Commun. 2017 Aug 24;8(1):350. doi: 10.1038/s41467-017-00429-3.
Nat Commun. 2017.
PMID: 28839146
Free PMC article.
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