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Year Number of Results
2013 5
2014 11
2015 7
2016 5
2017 1
2018 2
2019 7
2020 2
2024 0

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Page 1
The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases.
Roatsch M, Hoffmann I, Abboud MI, Hancock RL, Tarhonskaya H, Hsu KF, Wilkins SE, Yeh TL, Lippl K, Serrer K, Moneke I, Ahrens TD, Robaa D, Wenzler S, Barthes NPF, Franz H, Sippl W, Lassmann S, Diederichs S, Schleicher E, Schofield CJ, Kawamura A, Schüle R, Jung M. Roatsch M, et al. ACS Chem Biol. 2019 Aug 16;14(8):1737-1750. doi: 10.1021/acschembio.9b00289. Epub 2019 Jul 19. ACS Chem Biol. 2019. PMID: 31287655
Studies on spiro[4.5]decanone prolyl hydroxylase domain inhibitors.
Holt-Martyn JP, Tumber A, Rahman MZ, Lippl K, Figg W Jr, McDonough MA, Chowdhury R, Schofield CJ. Holt-Martyn JP, et al. Medchemcomm. 2019 Mar 1;10(4):500-504. doi: 10.1039/c8md00548f. eCollection 2019 Apr 1. Medchemcomm. 2019. PMID: 31057728 Free PMC article. Review.
Inhibition of a viral prolyl hydroxylase.
Langley GW, Abboud MI, Lohans CT, Schofield CJ. Langley GW, et al. Bioorg Med Chem. 2019 Jun 15;27(12):2405-2412. doi: 10.1016/j.bmc.2019.01.018. Epub 2019 Jan 23. Bioorg Med Chem. 2019. PMID: 30737136
Non-competitive cyclic peptides for targeting enzyme-substrate complexes.
McAllister TE, Yeh TL, Abboud MI, Leung IKH, Hookway ES, King ONF, Bhushan B, Williams ST, Hopkinson RJ, Münzel M, Loik ND, Chowdhury R, Oppermann U, Claridge TDW, Goto Y, Suga H, Schofield CJ, Kawamura A. McAllister TE, et al. Chem Sci. 2018 Apr 23;9(20):4569-4578. doi: 10.1039/c8sc00286j. eCollection 2018 May 28. Chem Sci. 2018. PMID: 29899950 Free PMC article.
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Yeh TL, Leissing TM, Abboud MI, Thinnes CC, Atasoylu O, Holt-Martyn JP, Zhang D, Tumber A, Lippl K, Lohans CT, Leung IKH, Morcrette H, Clifton IJ, Claridge TDW, Kawamura A, Flashman E, Lu X, Ratcliffe PJ, Chowdhury R, Pugh CW, Schofield CJ. Yeh TL, et al. Chem Sci. 2017 Nov 1;8(11):7651-7668. doi: 10.1039/c7sc02103h. Epub 2017 Sep 11. Chem Sci. 2017. PMID: 29435217 Free PMC article.
33 results