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Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE-/- mouse model of atherosclerosis with alterations in IL10/AMPKα pathway.
Thompson D, Morrice N, Grant L, Le Sommer S, Ziegler K, Whitfield P, Mody N, Wilson HM, Delibegović M. Thompson D, et al. Mol Metab. 2017 Jun 13;6(8):845-853. doi: 10.1016/j.molmet.2017.06.003. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752048 Free PMC article.
Neuronal human BACE1 knockin induces systemic diabetes in mice.
Plucińska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield PD, Doherty MK, Mingarelli M, Welch A, Riedel G, Delibegovic M, Platt B. Plucińska K, et al. Diabetologia. 2016 Jul;59(7):1513-1523. doi: 10.1007/s00125-016-3960-1. Epub 2016 May 2. Diabetologia. 2016. PMID: 27138913 Free PMC article.
Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue.
Mcilroy GD, Tammireddy SR, Maskrey BH, Grant L, Doherty MK, Watson DG, Delibegović M, Whitfield PD, Mody N. Mcilroy GD, et al. Biochem Pharmacol. 2016 Jan 15;100:86-97. doi: 10.1016/j.bcp.2015.11.017. Epub 2015 Nov 22. Biochem Pharmacol. 2016. PMID: 26592777 Free PMC article.
19 results