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Loss of interstitial collagen causes structural and functional alterations of cardiomyocyte subsarcolemmal mitochondria in acute volume overload.
Ulasova E, Gladden JD, Chen Y, Zheng J, Pat B, Bradley W, Powell P, Zmijewski JW, Zelickson BR, Ballinger SW, Darley-Usmar V, Dell'italia LJ. Ulasova E, et al. J Mol Cell Cardiol. 2011 Jan;50(1):147-56. doi: 10.1016/j.yjmcc.2010.10.034. Epub 2010 Nov 6. J Mol Cell Cardiol. 2011. PMID: 21059354 Free PMC article.
Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation.
Pat B, Chen Y, Killingsworth C, Gladden JD, Shi K, Zheng J, Powell PC, Walcott G, Ahmed MI, Gupta H, Desai R, Wei CC, Hase N, Kobayashi T, Sabri A, Granzier H, Denney T, Tillson M, Dillon AR, Husain A, Dell'italia LJ. Pat B, et al. Circulation. 2010 Oct 12;122(15):1488-95. doi: 10.1161/CIRCULATIONAHA.109.921619. Epub 2010 Sep 27. Circulation. 2010. PMID: 20876440 Free PMC article.
23 results