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Page 1
Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection.
Kerr CM, Pfannenstiel JJ, Alhammad YM, Roy A, O'Connor JJ, Ghimire R, Khattabi R, Shrestha R, McDonald PR, Gao P, Johnson DK, More S, Channappanavar R, Fehr AR. Kerr CM, et al. bioRxiv [Preprint]. 2024 Jan 4:2024.01.03.574082. doi: 10.1101/2024.01.03.574082. bioRxiv. 2024. PMID: 38260573 Free PMC article. Preprint.
Engineering a dual vaccine against COVID-19 and tuberculosis.
Guthrie CM, Tan X, Meeker AC, Self AE, Liu L, Cheng Y. Guthrie CM, et al. Front Cell Infect Microbiol. 2023 Oct 26;13:1273019. doi: 10.3389/fcimb.2023.1273019. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37965265 Free PMC article.
SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice.
Alhammad YM, Parthasarathy S, Ghimire R, Kerr CM, O'Connor JJ, Pfannenstiel JJ, Chanda D, Miller CA, Baumlin N, Salathe M, Unckless RL, Zuñiga S, Enjuanes L, More S, Channappanavar R, Fehr AR. Alhammad YM, et al. Proc Natl Acad Sci U S A. 2023 Aug 29;120(35):e2302083120. doi: 10.1073/pnas.2302083120. Epub 2023 Aug 22. Proc Natl Acad Sci U S A. 2023. PMID: 37607224 Free PMC article.
147 results