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Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation.
Goth CK, Mehta AY, McQuillan AM, Baker KJ, Hanes MS, Park SS, Stavenhagen K, Hjortø GM, Heimburg-Molinaro J, Chaikof EL, Rosenkilde MM, Cummings RD. Goth CK, et al. Cell Chem Biol. 2023 Aug 17;30(8):893-905.e7. doi: 10.1016/j.chembiol.2023.06.013. Epub 2023 Jul 17. Cell Chem Biol. 2023. PMID: 37463583
Structural basis for Lewis antigen synthesis by the α1,3-fucosyltransferase FUT9.
Kadirvelraj R, Boruah BM, Wang S, Chapla D, Huang C, Ramiah A, Hudson KL, Prudden AR, Boons GJ, Withers SG, Wood ZA, Moremen KW. Kadirvelraj R, et al. Nat Chem Biol. 2023 Aug;19(8):1022-1030. doi: 10.1038/s41589-023-01345-y. Epub 2023 May 18. Nat Chem Biol. 2023. PMID: 37202521 Free PMC article.
Modulation of Siglec-7 Signaling Via In Situ-Created High-Affinity cis-Ligands.
Hong S, Yu C, Rodrigues E, Shi Y, Chen H, Wang P, Chapla DG, Gao T, Zhuang R, Moremen KW, Paulson JC, Macauley MS, Wu P. Hong S, et al. ACS Cent Sci. 2021 Aug 25;7(8):1338-1346. doi: 10.1021/acscentsci.1c00064. Epub 2021 Aug 13. ACS Cent Sci. 2021. PMID: 34471678 Free PMC article.
75 results