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2007 1
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Page 1
Going beyond Binary: Rapid Identification of Protein-Protein Interaction Modulators Using a Multifragment Kinetic Target-Guided Synthesis Approach.
Nacheva K, Kulkarni SS, Kassu M, Flanigan D, Monastyrskyi A, Iyamu ID, Doi K, Barber M, Namelikonda N, Tipton JD, Parvatkar P, Wang HG, Manetsch R. Nacheva K, et al. J Med Chem. 2023 Apr 13;66(7):5196-5207. doi: 10.1021/acs.jmedchem.3c00108. Epub 2023 Mar 31. J Med Chem. 2023. PMID: 37000900 Free PMC article.
Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation.
Doi K, Li R, Sung SS, Wu H, Liu Y, Manieri W, Krishnegowda G, Awwad A, Dewey A, Liu X, Amin S, Cheng C, Qin Y, Schonbrunn E, Daughdrill G, Loughran TP Jr, Sebti S, Wang HG. Doi K, et al. J Biol Chem. 2012 Mar 23;287(13):10224-10235. doi: 10.1074/jbc.M111.334532. Epub 2012 Feb 6. J Biol Chem. 2012. PMID: 22311987 Free PMC article.
Abnormal MDMX degradation in tumor cells due to ARF deficiency.
Li X, Gilkes D, Li B, Cheng Q, Pernazza D, Lawrence H, Lawrence N, Chen J. Li X, et al. Oncogene. 2012 Aug 9;31(32):3721-32. doi: 10.1038/onc.2011.534. Epub 2011 Nov 28. Oncogene. 2012. PMID: 22120712 Free PMC article.
38 results