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TYK2 licenses non-canonical inflammasome activation during endotoxemia.
Poelzl A, Lassnig C, Tangermann S, Hromadová D, Reichart U, Gawish R, Mueller K, Moriggl R, Linkermann A, Glösmann M, Kenner L, Mueller M, Strobl B. Poelzl A, et al. Cell Death Differ. 2021 Feb;28(2):748-763. doi: 10.1038/s41418-020-00621-x. Epub 2020 Sep 14. Cell Death Differ. 2021. PMID: 32929218 Free PMC article.
Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue.
Castiglia V, Piersigilli A, Ebner F, Janos M, Goldmann O, Damböck U, Kröger A, Weiss S, Knapp S, Jamieson AM, Kirschning C, Kalinke U, Strobl B, Müller M, Stoiber D, Lienenklaus S, Kovarik P. Castiglia V, et al. Cell Host Microbe. 2016 Mar 9;19(3):375-87. doi: 10.1016/j.chom.2016.02.003. Cell Host Microbe. 2016. PMID: 26962946 Free article.
The good and the bad faces of STAT1 in solid tumours.
Meissl K, Macho-Maschler S, Müller M, Strobl B. Meissl K, et al. Cytokine. 2017 Jan;89:12-20. doi: 10.1016/j.cyto.2015.11.011. Epub 2015 Nov 26. Cytokine. 2017. PMID: 26631912 Free article. Review.
In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity.
Prchal-Murphy M, Witalisz-Siepracka A, Bednarik KT, Putz EM, Gotthardt D, Meissl K, Sexl V, Müller M, Strobl B. Prchal-Murphy M, et al. Oncoimmunology. 2015 May 26;4(11):e1047579. doi: 10.1080/2162402X.2015.1047579. eCollection 2015 Nov. Oncoimmunology. 2015. PMID: 26451322 Free PMC article.