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Results of phase 2 randomized multi-center study to evaluate the safety and efficacy of infusion of memory T cells as adoptive therapy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia and/or lymphopenia (RELEASE NCT04578210).
Ferreras C, Hernández-Blanco C, Martín-Quirós A, Al-Akioui-Sanz K, Mora-Rillo M, Ibáñez F, Díaz-Almirón M, Cano-Ochando J, Lozano-Ojalvo D, Jiménez-González M, Goterris R, Sánchez-Zapardiel E, de Paz R, Guerra-García P, Queiruga-Parada J, Molina P, Briones ML, Ruz-Caracuel B, Borobia AM, Carcas AJ, Planelles D, Vicario JL, Moreno MÁ, Balas A, Llano M, Llorente A, Del Balzo Á, Cañada C, García MÁ, Calvin ME, Arenas I, Pérez de Diego R, Eguizábal C, Soria B, Solano C, Pérez-Martínez A. Ferreras C, et al. Cytotherapy. 2024 Jan;26(1):25-35. doi: 10.1016/j.jcyt.2023.10.002. Epub 2023 Oct 29. Cytotherapy. 2024. PMID: 37897472 Clinical Trial.
Familial CD45RA- T cells to treat severe refractory infections in immunocompromised patients.
Al-Akioui Sanz K, Echecopar Parente C, Ferreras C, Menéndez Ribes M, Navarro A, Mestre C, Clares L, Vicario JL, Balas A, De Paz R, López Granados E, Sánchez Zapardiel E, Jiménez C, López-Oliva M, Ramos E, Hernández-Oliveros F, Pérez-Martínez A. Al-Akioui Sanz K, et al. Front Med (Lausanne). 2023 Feb 8;10:1083215. doi: 10.3389/fmed.2023.1083215. eCollection 2023. Front Med (Lausanne). 2023. PMID: 36844219 Free PMC article.
Inherited human ezrin deficiency impairs adaptive immunity.
García-Solís B, Van Den Rym A, Martinez-Martínez L, Franco T, Pérez-Caraballo JJ, Markle J, Cubillos-Zapata C, Marín AV, Recio MJ, Regueiro JR, Navarro-Zapata A, Mestre-Durán C, Ferreras C, Martín Cotázar C, Mena R, de la Calle-Fabregat C, López-Lera A, Fernández Arquero M, Pérez-Martínez A, López-Collazo E, Sánchez-Ramón S, Casanova JL, Martínez-Barricarte R, de la Calle-Martín O, Pérez de Diego R. García-Solís B, et al. J Allergy Clin Immunol. 2023 Oct;152(4):997-1009.e11. doi: 10.1016/j.jaci.2023.05.022. Epub 2023 Jun 8. J Allergy Clin Immunol. 2023. PMID: 37301410 Free PMC article.
Clinical research with targeted drugs in paediatric oncology.
Valle-Simón P, Borobia AM, Pérez-Martínez A. Valle-Simón P, et al. Drug Discov Today. 2023 Aug;28(8):103672. doi: 10.1016/j.drudis.2023.103672. Epub 2023 Jun 16. Drug Discov Today. 2023. PMID: 37330039 Review.
Rationale for combined therapies in severe-to-critical COVID-19 patients.
Gonzaga A, Andreu E, Hernández-Blasco LM, Meseguer R, Al-Akioui-Sanz K, Soria-Juan B, Sanjuan-Gimenez JC, Ferreras C, Tejedo JR, Lopez-Lluch G, Goterris R, Maciá L, Sempere-Ortells JM, Hmadcha A, Borobia A, Vicario JL, Bonora A, Aguilar-Gallardo C, Poveda JL, Arbona C, Alenda C, Tarín F, Marco FM, Merino E, Jaime F, Ferreres J, Figueira JC, Cañada-Illana C, Querol S, Guerreiro M, Eguizabal C, Martín-Quirós A, Robles-Marhuenda Á, Pérez-Martínez A, Solano C, Soria B. Gonzaga A, et al. Front Immunol. 2023 Sep 11;14:1232472. doi: 10.3389/fimmu.2023.1232472. eCollection 2023. Front Immunol. 2023. PMID: 37767093 Free PMC article. Review.
The challenge of standardizing CAR-T cell monitoring: A comparison of two flow-cytometry methods and correlation with qPCR technique.
Valdivieso-Shephard JL, Matas-Pérez E, García-Bujalance S, Mirones-Aguilar I, González-Martínez B, Pérez-Martínez A, López-Granados E, Martínez-Feito A, Sánchez-Zapardiel E. Valdivieso-Shephard JL, et al. Among authors: perez martinez a. Cytometry A. 2024 Feb 7. doi: 10.1002/cyto.a.24825. Online ahead of print. Cytometry A. 2024. PMID: 38327134
Neuropsychological and biopsychosocial evolution, therapeutic adherence and unmet care needs during paediatric transplantation: study protocol of a mixed-methods design (observational cohort study and focus groups) - the TransplantKIDS mental health project.
Garrido-Bolton J, Alcamí-Pertejo M, de la Vega R, Hernández-Oliveros F, Pérez-Martínez A, Bravo-Ortiz MF, Fernández-Jiménez E. Garrido-Bolton J, et al. Among authors: perez martinez a. Front Psychol. 2024 Feb 21;15:1308418. doi: 10.3389/fpsyg.2024.1308418. eCollection 2024. Front Psychol. 2024. PMID: 38449767 Free PMC article.
[Immunotherapy with CAR-T cells in paediatric haematology-oncology].
Mirones I, Moreno L, Patiño-García A, Lizeaga G, Moraleda JM, Toribio ML, Pérez-Martínez A; Grupo de Inmunoterapia y Terapias Avanzadas de la Sociedad Española de Hematología y Oncología Pediátricas; Grupo de Inmunoterapia y Terapias Avanzadas de la Sociedad Española de Hematología y Oncología Pediátricas. Mirones I, et al. An Pediatr (Engl Ed). 2020 Jul;93(1):59.e1-59.e10. doi: 10.1016/j.anpedi.2019.12.014. Epub 2020 Feb 24. An Pediatr (Engl Ed). 2020. PMID: 32107177 Free article. Spanish.
Corrigendum: Impact of disease burden and late loss of B cell aplasia on the risk of relapse after CD19 chimeric antigen receptor T Cell (Tisagenlecleucel) infusion in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia: role of B-cell monitoring.
Molinos-Quintana Á, Alonso-Saladrigues A, Herrero B, Caballero-Velázquez T, Galán-Gómez V, Panesso M, Torrebadell M, Delgado-Serrano J, Pérez de Soto C, Faura A, González-Martínez B, Castillo-Robleda A, Diaz-de-Heredia C, Pérez-Martínez A, Pérez-Hurtado JM, Rives S, Pérez-Simón JA. Molinos-Quintana Á, et al. Among authors: perez martinez a. Front Immunol. 2024 Feb 7;15:1373852. doi: 10.3389/fimmu.2024.1373852. eCollection 2024. Front Immunol. 2024. PMID: 38384474 Free PMC article.
291 results