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Discovery and characterization of an endogenous CXCR4 antagonist.
Zirafi O, Kim KA, Ständker L, Mohr KB, Sauter D, Heigele A, Kluge SF, Wiercinska E, Chudziak D, Richter R, Moepps B, Gierschik P, Vas V, Geiger H, Lamla M, Weil T, Burster T, Zgraja A, Daubeuf F, Frossard N, Hachet-Haas M, Heunisch F, Reichetzeder C, Galzi JL, Pérez-Castells J, Canales-Mayordomo A, Jiménez-Barbero J, Giménez-Gallego G, Schneider M, Shorter J, Telenti A, Hocher B, Forssmann WG, Bonig H, Kirchhoff F, Münch J. Zirafi O, et al. Cell Rep. 2015 May 5;11(5):737-47. doi: 10.1016/j.celrep.2015.03.061. Epub 2015 Apr 23. Cell Rep. 2015. PMID: 25921529 Free article.
CgNa, a type I toxin from the giant Caribbean sea anemone Condylactis gigantea shows structural similarities to both type I and II toxins, as well as distinctive structural and functional properties(1).
Salceda E, Pérez-Castells J, López-Méndez B, Garateix A, Salazar H, López O, Aneiros A, Ständker L, Béress L, Forssmann WG, Soto E, Jiménez-Barbero J, Giménez-Gallego G. Salceda E, et al. Biochem J. 2007 Aug 15;406(1):67-76. doi: 10.1042/BJ20070130. Biochem J. 2007. PMID: 17506725 Free PMC article.
Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide.
Forssmann WG, The YH, Stoll M, Adermann K, Albrecht U, Tillmann HC, Barlos K, Busmann A, Canales-Mayordomo A, Giménez-Gallego G, Hirsch J, Jiménez-Barbero J, Meyer-Olson D, Münch J, Pérez-Castells J, Ständker L, Kirchhoff F, Schmidt RE. Forssmann WG, et al. Sci Transl Med. 2010 Dec 22;2(63):63re3. doi: 10.1126/scitranslmed.3001697. Sci Transl Med. 2010. PMID: 21178138 Clinical Trial.
Avenues to Characterize the Interactions of Extended N-Glycans with Proteins by NMR Spectroscopy: The Influenza Hemagglutinin Case.
Fernández de Toro B, Peng W, Thompson AJ, Domínguez G, Cañada FJ, Pérez-Castells J, Paulson JC, Jiménez-Barbero J, Canales Á. Fernández de Toro B, et al. Angew Chem Int Ed Engl. 2018 Nov 12;57(46):15051-15055. doi: 10.1002/anie.201807162. Epub 2018 Oct 17. Angew Chem Int Ed Engl. 2018. PMID: 30238596 Free PMC article.
Lanthanide-chelating carbohydrate conjugates are useful tools to characterize carbohydrate conformation in solution and sensitive sensors to detect carbohydrate-protein interactions.
Canales Á, Mallagaray Á, Berbís MÁ, Navarro-Vázquez A, Domínguez G, Cañada FJ, André S, Gabius HJ, Pérez-Castells J, Jiménez-Barbero J. Canales Á, et al. J Am Chem Soc. 2014 Jun 4;136(22):8011-7. doi: 10.1021/ja502406x. Epub 2014 May 27. J Am Chem Soc. 2014. PMID: 24831588
48 results