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BRAF activation by metabolic stress promotes glycolysis sensitizing NRASQ61-mutated melanomas to targeted therapy.
McGrail K, Granado-Martínez P, Esteve-Puig R, García-Ortega S, Ding Y, Sánchez-Redondo S, Ferrer B, Hernandez-Losa J, Canals F, Manzano A, Navarro-Sabaté A, Bartrons R, Yanes O, Pérez-Alea M, Muñoz-Couselo E, Garcia-Patos V, Recio JA. McGrail K, et al. Among authors: perez alea m. Nat Commun. 2022 Nov 19;13(1):7113. doi: 10.1038/s41467-022-34907-0. Nat Commun. 2022. PMID: 36402789 Free PMC article.
Dual disruption of aldehyde dehydrogenases 1 and 3 promotes functional changes in the glutathione redox system and enhances chemosensitivity in nonsmall cell lung cancer.
Rebollido-Rios R, Venton G, Sánchez-Redondo S, Iglesias I Felip C, Fournet G, González E, Romero Fernández W, Borroto Escuela DO, Di Stefano B, Penarroche-Díaz R, Martin G, Ceylan I, Costello R, Perez-Alea M. Rebollido-Rios R, et al. Among authors: perez alea m. Oncogene. 2020 Mar;39(13):2756-2771. doi: 10.1038/s41388-020-1184-9. Epub 2020 Feb 3. Oncogene. 2020. PMID: 32015486 Free PMC article.
Genetic Profiles of Squamous Cell Carcinomas Associated with Recessive Dystrophic Epidermolysis Bullosa Unveil NOTCH and TP53 Mutations and an Increased MYC Expression.
Sans-DeSanNicolas L, Caratú G, Vidal-Cortés O, Sanchez-Redondo S, Ferrer B, Mancuso F, González-Sanchez E, Pérez-Alea M, McGrail K, Hernandez-Losa J, Bodet D, Vivancos A, Garcia-Patos V, Recio JA. Sans-DeSanNicolas L, et al. Among authors: perez alea m. J Invest Dermatol. 2018 Jun;138(6):1423-1427. doi: 10.1016/j.jid.2017.12.026. Epub 2017 Dec 29. J Invest Dermatol. 2018. PMID: 29291383 Free article. No abstract available.
Disruption of the ribosomal P complex leads to stress-induced autophagy.
Artero-Castro A, Perez-Alea M, Feliciano A, Leal JA, Genestar M, Castellvi J, Peg V, Ramón Y Cajal S, Lleonart ME. Artero-Castro A, et al. Among authors: perez alea m. Autophagy. 2015;11(9):1499-519. doi: 10.1080/15548627.2015.1063764. Autophagy. 2015. PMID: 26176264 Free PMC article.
Enhancement of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems. Relevance for neuroplasticity and depression.
Borroto-Escuela DO, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Jiménez-Beristain A, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Borroto-Escuela DO, et al. Among authors: perez alea m. Biochem Biophys Res Commun. 2015 Jul 31;463(3):180-6. doi: 10.1016/j.bbrc.2015.04.133. Epub 2015 May 6. Biochem Biophys Res Commun. 2015. PMID: 25957476 Free article.
22 results