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1-(2',5'-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A Positive Allosteric Modulator of α7 Nicotinic Receptors with Analgesic and Neuroprotective Activity.
Pérez de Vega MJ, Fernandez-Mendivil C, de la Torre Martínez R, González-Rodríguez S, Mullet J, Sala F, Sala S, Criado M, Moreno-Fernández S, Miguel M, Fernández-Carvajal A, Ferrer-Montiel A, López MG, González-Muñiz R. Pérez de Vega MJ, et al. ACS Chem Neurosci. 2019 Aug 21;10(8):3900-3909. doi: 10.1021/acschemneuro.9b00364. Epub 2019 Aug 2. ACS Chem Neurosci. 2019. PMID: 31322853 Free article.
Parallel solid-phase synthesis of a small library of linear and hydrocarbon-bridged analogues of VEGF(81-91): potential biological tools for studying the VEGF/VEGFR-1 interaction.
García-Aranda MI, Marrero P, Gautier B, Martín-Martínez M, Inguimbert N, Vidal M, García-López MT, Jiménez MA, González-Muñiz R, Pérez de Vega MJ. García-Aranda MI, et al. Among authors: perez de vega mj. Bioorg Med Chem. 2011 Mar 15;19(6):1978-86. doi: 10.1016/j.bmc.2011.01.056. Epub 2011 Feb 2. Bioorg Med Chem. 2011. PMID: 21349728
Disulfide and amide-bridged cyclic peptide analogues of the VEGF₈₁₋₉₁ fragment: synthesis, conformational analysis and biological evaluation.
García-Aranda MI, Mirassou Y, Gautier B, Martín-Martínez M, Inguimbert N, Vidal M, García-López MT, Jiménez MA, González-Muñiz R, Pérez de Vega MJ. García-Aranda MI, et al. Among authors: perez de vega mj. Bioorg Med Chem. 2011 Dec 15;19(24):7526-33. doi: 10.1016/j.bmc.2011.10.032. Epub 2011 Oct 18. Bioorg Med Chem. 2011. PMID: 22078412
Helical peptides from VEGF and Vammin hotspots for modulating the VEGF-VEGFR interaction.
García-Aranda MI, González-López S, Santiveri CM, Gagey-Eilstein N, Reille-Seroussi M, Martín-Martínez M, Inguimbert N, Vidal M, García-López MT, Jiménez MA, González-Muñiz R, Pérez de Vega MJ. García-Aranda MI, et al. Among authors: perez de vega mj. Org Biomol Chem. 2013 Mar 21;11(11):1896-905. doi: 10.1039/c3ob27312a. Epub 2013 Feb 4. Org Biomol Chem. 2013. PMID: 23381088
Chalcones as positive allosteric modulators of α7 nicotinic acetylcholine receptors: a new target for a privileged structure.
Balsera B, Mulet J, Fernández-Carvajal A, de la Torre-Martínez R, Ferrer-Montiel A, Hernández-Jiménez JG, Estévez-Herrera J, Borges R, Freitas AE, López MG, García-López MT, González-Muñiz R, Pérez de Vega MJ, Valor LM, Svobodová L, Sala S, Sala F, Criado M. Balsera B, et al. Among authors: de la torre martinez r, perez de vega mj. Eur J Med Chem. 2014 Oct 30;86:724-39. doi: 10.1016/j.ejmech.2014.09.039. Epub 2014 Sep 16. Eur J Med Chem. 2014. PMID: 25232969
1,3-diphenylpropan-1-ones as allosteric modulators of α7 nACh receptors with analgesic and antioxidant properties.
Criado M, Balsera B, Mulet J, Sala S, Sala F, de la Torre-Martínez R, Fernández-Carvajal A, Ferrer-Montiel A, Moreno-Fernández S, Miguel M, Pérez de Vega MJ, González-Muñiz R. Criado M, et al. Among authors: de la torre martinez r, perez de vega mj. Future Med Chem. 2016 May;8(7):731-49. doi: 10.4155/fmc-2015-0001. Epub 2016 May 10. Future Med Chem. 2016. PMID: 27161515 Free article.
Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of α7 nicotinic receptors with analgesic activity.
Balsera B, Mulet J, Sala S, Sala F, de la Torre-Martínez R, González-Rodríguez S, Plata A, Naesens L, Fernández-Carvajal A, Ferrer-Montiel A, Criado M, Pérez de Vega MJ, González-Muñiz R. Balsera B, et al. Among authors: perez de vega mj. Eur J Med Chem. 2018 Jan 1;143:157-165. doi: 10.1016/j.ejmech.2017.10.083. Epub 2017 Nov 2. Eur J Med Chem. 2018. PMID: 29174812
30 results