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Page 1
CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer.
Tejedor JR, Peñarroya A, Gancedo-Verdejo J, Santamarina-Ojeda P, Pérez RF, López-Tamargo S, Díez-Borge A, Alba-Linares JJ, González-Del-Rey N, Urdinguio RG, Mangas C, Roberti A, López V, Morales-Ruiz T, Ariza RR, Roldán-Arjona T, Meijón M, Valledor L, Cañal MJ, Fernández-Martínez D, Fernández-Hevia M, Jiménez-Fonseca P, García-Flórez LJ, Fernández AF, Fraga MF. Tejedor JR, et al. Among authors: perez rf. Clin Epigenetics. 2023 Aug 24;15(1):133. doi: 10.1186/s13148-023-01546-1. Clin Epigenetics. 2023. PMID: 37612734 Free PMC article.
SDHC Promoter Methylation, a Novel Pathogenic Mechanism in Parasympathetic Paragangliomas.
Bernardo-Castiñeira C, Valdés N, Sierra MI, Sáenz-de-Santa-María I, Bayón GF, Perez RF, Fernández AF, Fraga MF, Astudillo A, Menéndez R, Fernández B, Del Olmo M, Suarez C, Chiara MD. Bernardo-Castiñeira C, et al. Among authors: perez rf. J Clin Endocrinol Metab. 2018 Jan 1;103(1):295-305. doi: 10.1210/jc.2017-01702. J Clin Endocrinol Metab. 2018. PMID: 29126304
Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma.
Fernandez AF, Bayón GF, Sierra MI, Urdinguio RG, Toraño EG, García MG, Carella A, López V, Santamarina P, Pérez RF, Belmonte T, Tejedor JR, Cobo I, Menendez P, Mangas C, Ferrero C, Rodrigo L, Astudillo A, Ortea I, Cueto Díaz S, Rodríguez-Gonzalez P, García Alonso JI, Mollejo M, Meléndez B, Domínguez G, Bonilla F, Fraga MF. Fernandez AF, et al. Among authors: perez rf. Hum Mol Genet. 2018 Sep 1;27(17):3046-3059. doi: 10.1093/hmg/ddy214. Hum Mol Genet. 2018. PMID: 29878202 Free article.
Epigenetic dysregulation of TET2 in human glioblastoma.
García MG, Carella A, Urdinguio RG, Bayón GF, Lopez V, Tejedor JR, Sierra MI, García-Toraño E, Santamarina P, Perez RF, Mangas C, Astudillo A, Corte-Torres MD, Sáenz-de-Santa-María I, Chiara MD, Fernández AF, Fraga MF. García MG, et al. Among authors: perez rf. Oncotarget. 2018 May 25;9(40):25922-25934. doi: 10.18632/oncotarget.25406. eCollection 2018 May 25. Oncotarget. 2018. PMID: 29899831 Free PMC article.
Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment.
Urdinguio RG, Lopez V, Bayón GF, Diaz de la Guardia R, Sierra MI, García-Toraño E, Perez RF, García MG, Carella A, Pruneda PC, Prieto C, Dmitrijeva M, Santamarina P, Belmonte T, Mangas C, Diaconu E, Ferrero C, Tejedor JR, Fernandez-Morera JL, Bravo C, Bueno C, Sanjuan-Pla A, Rodriguez RM, Suarez-Alvarez B, López-Larrea C, Bernal T, Colado E, Balbín M, García-Suarez O, Chiara MD, Sáenz-de-Santa-María I, Rodríguez F, Pando-Sandoval A, Rodrigo L, Santos L, Salas A, Vallejo-Díaz J, C Carrera A, Rico D, Hernández-López I, Vayá A, Ricart JM, Seto E, Sima-Teruel N, Vaquero A, Valledor L, Cañal MJ, Pisano D, Graña-Castro O, Thomas T, Voss AK, Menéndez P, Villar-Garea A, Deutzmann R, Fernandez AF, Fraga MF. Urdinguio RG, et al. Among authors: perez rf. Nucleic Acids Res. 2019 Jun 4;47(10):5016-5037. doi: 10.1093/nar/gkz195. Nucleic Acids Res. 2019. PMID: 30923829 Free PMC article.
Epigenetic downregulation of TET3 reduces genome-wide 5hmC levels and promotes glioblastoma tumorigenesis.
Carella A, Tejedor JR, García MG, Urdinguio RG, Bayón GF, Sierra M, López V, García-Toraño E, Santamarina-Ojeda P, Pérez RF, Bigot T, Mangas C, Corte-Torres MD, Sáenz-de-Santa-María I, Mollejo M, Meléndez B, Astudillo A, Chiara MD, Fernández AF, Fraga MF. Carella A, et al. Among authors: perez rf. Int J Cancer. 2020 Jan 15;146(2):373-387. doi: 10.1002/ijc.32520. Epub 2019 Jul 1. Int J Cancer. 2020. PMID: 31211412 Free article.
No genome-wide DNA methylation changes found associated with medium-term reduced graphene oxide exposure in human lung epithelial cells.
Pérez RF, Soto Fernández AY, Bousquets Muñoz P, Sierra MI, Tejedor JR, Morales-Sánchez P, Valdés AF, Santamaría R, Blanco C, Torrecillas R, Fraga MF, Fernández AF. Pérez RF, et al. Epigenetics. 2020 Mar;15(3):283-293. doi: 10.1080/15592294.2019.1666650. Epub 2019 Sep 18. Epigenetics. 2020. PMID: 31512544 Free PMC article.
29 results