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Neurogenic Potential Assessment and Pharmacological Characterization of 6-Methoxy-1,2,3,4-tetrahydro-β-carboline (Pinoline) and Melatonin-Pinoline Hybrids.
de la Fuente Revenga M, Pérez C, Morales-García JA, Alonso-Gil S, Pérez-Castillo A, Caignard DH, Yáñez M, Gamo AM, Rodríguez-Franco MI. de la Fuente Revenga M, et al. Among authors: perez castillo a, perez c. ACS Chem Neurosci. 2015 May 20;6(5):800-10. doi: 10.1021/acschemneuro.5b00041. Epub 2015 Apr 9. ACS Chem Neurosci. 2015. PMID: 25815906
New melatonin-N,N-dibenzyl(N-methyl)amine hybrids: potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease.
López-Iglesias B, Pérez C, Morales-García JA, Alonso-Gil S, Pérez-Castillo A, Romero A, López MG, Villarroya M, Conde S, Rodríguez-Franco MI. López-Iglesias B, et al. Among authors: perez castillo a, perez c. J Med Chem. 2014 May 8;57(9):3773-85. doi: 10.1021/jm5000613. Epub 2014 Apr 28. J Med Chem. 2014. PMID: 24738476
Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.
Estrada Valencia M, Herrera-Arozamena C, de Andrés L, Pérez C, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Viña D, Yáñez M, Laurini E, Pricl S, Rodríguez-Franco MI. Estrada Valencia M, et al. Among authors: perez castillo a, perez c. Eur J Med Chem. 2018 Aug 5;156:534-553. doi: 10.1016/j.ejmech.2018.07.026. Epub 2018 Jul 11. Eur J Med Chem. 2018. PMID: 30025348 Free article.
Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties.
Herrera-Arozamena C, Estrada-Valencia M, Pérez C, Lagartera L, Morales-García JA, Pérez-Castillo A, Franco-Gonzalez JF, Michalska P, Duarte P, León R, López MG, Mills A, Gago F, García-Yagüe ÁJ, Fernández-Ginés R, Cuadrado A, Rodríguez-Franco MI. Herrera-Arozamena C, et al. Among authors: perez castillo a, perez c. Eur J Med Chem. 2020 Mar 15;190:112090. doi: 10.1016/j.ejmech.2020.112090. Epub 2020 Jan 25. Eur J Med Chem. 2020. PMID: 32018096 Free article.
Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties.
Fernández-Bachiller MI, Pérez C, Campillo NE, Páez JA, González-Muñoz GC, Usán P, García-Palomero E, López MG, Villarroya M, García AG, Martínez A, Rodríguez-Franco MI. Fernández-Bachiller MI, et al. Among authors: perez c. ChemMedChem. 2009 May;4(5):828-41. doi: 10.1002/cmdc.200800414. ChemMedChem. 2009. PMID: 19308922
New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties.
Estrada M, Herrera-Arozamena C, Pérez C, Viña D, Romero A, Morales-García JA, Pérez-Castillo A, Rodríguez-Franco MI. Estrada M, et al. Among authors: perez castillo a, perez c. Eur J Med Chem. 2016 Oct 4;121:376-386. doi: 10.1016/j.ejmech.2016.05.055. Epub 2016 May 25. Eur J Med Chem. 2016. PMID: 27267007 Free article.
3,519 results