Pääbo S - Search Results

1

Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals.

Ågren R, Patil S, Zhou X; FinnGen.; Sahlholm K, Pääbo S, Zeberg H. Ågren R, et al. Among authors: paabo s. Mol Biol Evol. 2023 Jun 1;40(6):msad130. doi: 10.1093/molbev/msad130. Mol Biol Evol. 2023. PMID: 37315093 Free PMC article.

2

Functional dissection of two amino acid substitutions unique to the human FOXP2 protein.

Bornschein U, Zeberg H, Enard W, Hevers W, Pääbo S. Bornschein U, et al. Among authors: paabo s. Sci Rep. 2023 Mar 6;13(1):3747. doi: 10.1038/s41598-023-30663-3. Sci Rep. 2023. PMID: 36879029 Free PMC article.

3

The genetic changes that shaped Neandertals, Denisovans, and modern humans.

Zeberg H, Jakobsson M, Pääbo S. Zeberg H, et al. Among authors: paabo s. Cell. 2024 Feb 29;187(5):1047-1058. doi: 10.1016/j.cell.2023.12.029. Epub 2024 Feb 16. Cell. 2024. PMID: 38367615 Review.

4

Detection of unintended on-target effects in CRISPR genome editing by DNA donors carrying diagnostic substitutions.

Lackner M, Helmbrecht N, Pääbo S, Riesenberg S. Lackner M, et al. Among authors: paabo s. Nucleic Acids Res. 2023 Mar 21;51(5):e26. doi: 10.1093/nar/gkac1254. Nucleic Acids Res. 2023. PMID: 36620901 Free PMC article.

5

The modern human aryl hydrocarbon receptor is more active when ancestralized by genome editing.

Helmbrecht N, Lackner M, Maricic T, Pääbo S. Helmbrecht N, et al. Among authors: paabo s. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2402159121. doi: 10.1073/pnas.2402159121. Epub 2024 May 13. Proc Natl Acad Sci U S A. 2024. PMID: 38739836

6

Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development.

Xing L, Gkini V, Nieminen AI, Zhou HC, Aquilino M, Naumann R, Reppe K, Tanaka K, Carmeliet P, Heikinheimo O, Pääbo S, Huttner WB, Namba T. Xing L, et al. Among authors: paabo s. Nat Commun. 2024 Apr 24;15(1):3468. doi: 10.1038/s41467-024-47437-8. Nat Commun. 2024. PMID: 38658571 Free PMC article.

7

Efficient high-precision homology-directed repair-dependent genome editing by HDRobust.

Riesenberg S, Kanis P, Macak D, Wollny D, Düsterhöft D, Kowalewski J, Helmbrecht N, Maricic T, Pääbo S. Riesenberg S, et al. Among authors: paabo s. Nat Methods. 2023 Sep;20(9):1388-1399. doi: 10.1038/s41592-023-01949-1. Epub 2023 Jul 20. Nat Methods. 2023. PMID: 37474806 Free PMC article.

8

Ancient human DNA recovered from a Palaeolithic pendant.

Essel E, Zavala EI, Schulz-Kornas E, Kozlikin MB, Fewlass H, Vernot B, Shunkov MV, Derevianko AP, Douka K, Barnes I, Soulier MC, Schmidt A, Szymanski M, Tsanova T, Sirakov N, Endarova E, McPherron SP, Hublin JJ, Kelso J, Pääbo S, Hajdinjak M, Soressi M, Meyer M. Essel E, et al. Among authors: paabo s. Nature. 2023 Jun;618(7964):328-332. doi: 10.1038/s41586-023-06035-2. Epub 2023 May 3. Nature. 2023. PMID: 37138083 Free PMC article.

9

Response to Comment on "Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals".

Pinson A, Maricic T, Zeberg H, Pääbo S, Huttner WB. Pinson A, et al. Among authors: paabo s. Science. 2023 Mar 10;379(6636):eadf2212. doi: 10.1126/science.adf2212. Epub 2023 Mar 10. Science. 2023. PMID: 36893240

10

The molecular evolution of spermatogenesis across mammals.

Murat F, Mbengue N, Winge SB, Trefzer T, Leushkin E, Sepp M, Cardoso-Moreira M, Schmidt J, Schneider C, Mößinger K, Brüning T, Lamanna F, Belles MR, Conrad C, Kondova I, Bontrop R, Behr R, Khaitovich P, Pääbo S, Marques-Bonet T, Grützner F, Almstrup K, Schierup MH, Kaessmann H. Murat F, et al. Among authors: paabo s. Nature. 2023 Jan;613(7943):308-316. doi: 10.1038/s41586-022-05547-7. Epub 2022 Dec 21. Nature. 2023. PMID: 36544022 Free PMC article.

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