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Discovery of senolytics using machine learning.
Smer-Barreto V, Quintanilla A, Elliott RJR, Dawson JC, Sun J, Campa VM, Lorente-Macías Á, Unciti-Broceta A, Carragher NO, Acosta JC, Oyarzún DA. Smer-Barreto V, et al. Among authors: oyarzun da. Nat Commun. 2023 Jun 10;14(1):3445. doi: 10.1038/s41467-023-39120-1. Nat Commun. 2023. PMID: 37301862 Free PMC article.
Pathways to cellular supremacy in biocomputing.
Grozinger L, Amos M, Gorochowski TE, Carbonell P, Oyarzún DA, Stoof R, Fellermann H, Zuliani P, Tas H, Goñi-Moreno A. Grozinger L, et al. Among authors: oyarzun da. Nat Commun. 2019 Nov 20;10(1):5250. doi: 10.1038/s41467-019-13232-z. Nat Commun. 2019. PMID: 31748511 Free PMC article. Review.
Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health.
Gadd DA, Hillary RF, McCartney DL, Shi L, Stolicyn A, Robertson NA, Walker RM, McGeachan RI, Campbell A, Xueyi S, Barbu MC, Green C, Morris SW, Harris MA, Backhouse EV, Wardlaw JM, Steele JD, Oyarzún DA, Muniz-Terrera G, Ritchie C, Nevado-Holgado A, Chandra T, Hayward C, Evans KL, Porteous DJ, Cox SR, Whalley HC, McIntosh AM, Marioni RE. Gadd DA, et al. Among authors: oyarzun da. Nat Commun. 2022 Aug 9;13(1):4670. doi: 10.1038/s41467-022-32319-8. Nat Commun. 2022. PMID: 35945220 Free PMC article.
Deep learning for optimization of protein expression.
Nikolados EM, Oyarzún DA. Nikolados EM, et al. Among authors: oyarzun da. Curr Opin Biotechnol. 2023 Jun;81:102941. doi: 10.1016/j.copbio.2023.102941. Epub 2023 Apr 21. Curr Opin Biotechnol. 2023. PMID: 37087839 Free article. Review.
Bayesian Optimization for Design of Multiscale Biological Circuits.
Merzbacher C, Mac Aodha O, Oyarzún DA. Merzbacher C, et al. Among authors: oyarzun da. ACS Synth Biol. 2023 Jul 21;12(7):2073-2082. doi: 10.1021/acssynbio.3c00120. Epub 2023 Jun 20. ACS Synth Biol. 2023. PMID: 37339382 Free PMC article.
Prediction of Cellular Burden with Host-Circuit Models.
Nikolados EM, Weiße AY, Oyarzún DA. Nikolados EM, et al. Among authors: oyarzun da. Methods Mol Biol. 2021;2229:267-291. doi: 10.1007/978-1-0716-1032-9_13. Methods Mol Biol. 2021. PMID: 33405227
40 results